| Title |
The Tre2 Oncoprotein, Implicated in Ewing’s Sarcoma, Interacts with Two Components of the Cytoskeleton
|
|---|---|
| Published in |
Biotechnology Techniques, February 2006
|
| DOI | 10.1007/s10529-005-5523-2 |
| Pubmed ID | |
| Authors |
Christophe Dechamps, Stephane Bach, Daniel Portetelle, Micheline Vandenbol |
| Abstract |
The product of the Tre2 oncogene, structurally related to the Ypt/RabGTPase-activating proteins (Ypt/RabGAP), is involved in various human cancers, including Ewing's sarcoma. In order to identify proteins interacting with the GAP part of this protein, we performed yeast two-hybrid screening of two libraries. Two components of the cytoskeleton were thus identified, whose interaction with the GAP region was confirmed by GST-pulldown, co-immunoprecipitation, and colocalisation experiments. The proteins found to interact with the GAP region are the light regulatory chain of myosin II (Myl2) and LOC91256, a protein containing ankyrin repeats. |
Mendeley readers
The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 10 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 5 | 50% |
| Student > Ph. D. Student | 3 | 30% |
| Professor > Associate Professor | 1 | 10% |
| Unknown | 1 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 6 | 60% |
| Biochemistry, Genetics and Molecular Biology | 3 | 30% |
| Unknown | 1 | 10% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 January 2020.
All research outputs
#8,543,833
of 25,394,764 outputs
Outputs from Biotechnology Techniques
#831
of 2,763 outputs
Outputs of similar age
#44,409
of 170,310 outputs
Outputs of similar age from Biotechnology Techniques
#13
of 18 outputs
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