| Title |
Sedentary behaviour and risk of all-cause, cardiovascular and cancer mortality, and incident type 2 diabetes: a systematic review and dose response meta-analysis
|
|---|---|
| Published in |
European Journal of Epidemiology, March 2018
|
| DOI | 10.1007/s10654-018-0380-1 |
| Pubmed ID | |
| Authors |
Richard Patterson, Eoin McNamara, Marko Tainio, Thiago Hérick de Sá, Andrea D. Smith, Stephen J. Sharp, Phil Edwards, James Woodcock, Søren Brage, Katrien Wijndaele |
| Abstract |
To estimate the strength and shape of the dose-response relationship between sedentary behaviour and all-cause, cardiovascular disease (CVD) and cancer mortality, and incident type 2 diabetes (T2D), adjusted for physical activity (PA). Data Sources: Pubmed, Web of Knowledge, Medline, Embase, Cochrane Library and Google Scholar (through September-2016); reference lists. Study Selection: Prospective studies reporting associations between total daily sedentary time or TV viewing time, and ≥ one outcome of interest. Data Extraction: Two independent reviewers extracted data, study quality was assessed; corresponding authors were approached where needed. Data Synthesis: Thirty-four studies (1,331,468 unique participants; good study quality) covering 8 exposure-outcome combinations were included. For total sedentary behaviour, the PA-adjusted relationship was non-linear for all-cause mortality (RR per 1 h/day: were 1.01 (1.00-1.01) ≤ 8 h/day; 1.04 (1.03-1.05) > 8 h/day of exposure), and for CVD mortality (1.01 (0.99-1.02) ≤ 6 h/day; 1.04 (1.03-1.04) > 6 h/day). The association was linear (1.01 (1.00-1.01)) with T2D and non-significant with cancer mortality. Stronger PA-adjusted associations were found for TV viewing (h/day); non-linear for all-cause mortality (1.03 (1.01-1.04) ≤ 3.5 h/day; 1.06 (1.05-1.08) > 3.5 h/day) and for CVD mortality (1.02 (0.99-1.04) ≤ 4 h/day; 1.08 (1.05-1.12) > 4 h/day). Associations with cancer mortality (1.03 (1.02-1.04)) and T2D were linear (1.09 (1.07-1.12)). Independent of PA, total sitting and TV viewing time are associated with greater risk for several major chronic disease outcomes. For all-cause and CVD mortality, a threshold of 6-8 h/day of total sitting and 3-4 h/day of TV viewing was identified, above which the risk is increased. |
X Demographics
The data shown below were collected from the profiles of 126 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 25 | 20% |
| Spain | 15 | 12% |
| United States | 6 | 5% |
| South Africa | 5 | 4% |
| Australia | 4 | 3% |
| Mexico | 3 | 2% |
| Canada | 3 | 2% |
| Japan | 2 | 2% |
| Brazil | 2 | 2% |
| Other | 13 | 10% |
| Unknown | 48 | 38% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 84 | 67% |
| Scientists | 20 | 16% |
| Practitioners (doctors, other healthcare professionals) | 18 | 14% |
| Science communicators (journalists, bloggers, editors) | 4 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 1,294 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1294 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 166 | 13% |
| Student > Bachelor | 158 | 12% |
| Student > Ph. D. Student | 113 | 9% |
| Researcher | 80 | 6% |
| Student > Doctoral Student | 67 | 5% |
| Other | 184 | 14% |
| Unknown | 526 | 41% |
| Readers by discipline | Count | As % |
|---|---|---|
| Sports and Recreations | 173 | 13% |
| Medicine and Dentistry | 168 | 13% |
| Nursing and Health Professions | 138 | 11% |
| Social Sciences | 33 | 3% |
| Psychology | 32 | 2% |
| Other | 159 | 12% |
| Unknown | 591 | 46% |
Attention Score in Context
This research output has an Altmetric Attention Score of 478. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 March 2024.
All research outputs
#56,760
of 26,017,215 outputs
Outputs from European Journal of Epidemiology
#21
of 1,885 outputs
Outputs of similar age
#1,329
of 348,171 outputs
Outputs of similar age from European Journal of Epidemiology
#1
of 35 outputs
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So far Altmetric has tracked 1,885 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 38.3. This one has done particularly well, scoring higher than 98% of its peers.
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We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.