| Title |
The first avian Ig-like Fc receptor family member combines features of mammalian FcR and FCRL
|
|---|---|
| Published in |
Immunogenetics, February 2007
|
| DOI | 10.1007/s00251-007-0195-9 |
| Pubmed ID | |
| Authors |
Alexander Iain Taylor, Hannah Jane Gould, Brian John Sutton, Rosaleen Ann Calvert |
| Abstract |
Homologues of almost all mammalian Ig-like immunoregulatory receptor families have been found in the chicken, except the Fc receptor (FcR) family. In addition to classical FcRs that specifically bind antibodies and mediate their effector functions, this family includes "Fc receptor-like" (FCRL) proteins for which ligands have yet to be identified. We have cloned and expressed a full-length chicken monocyte transcript that encodes an avian homologue of the mammalian FcR family. We have termed it chFcR/L as it possesses characteristics of both mammalian FcR and FCRL, but is phylogenetically distinct from either. chFcR/L is a transmembrane protein with four extracellular Ig-like domains and a short cytoplasmic tail. It can be expressed on the cell surface only in the presence of an accessory molecule, chFcRgamma, through which it acquires signalling potential. |
Mendeley readers
The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Austria | 1 | 7% |
| Unknown | 14 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 4 | 27% |
| Student > Master | 4 | 27% |
| Researcher | 3 | 20% |
| Student > Doctoral Student | 2 | 13% |
| Unknown | 2 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 6 | 40% |
| Biochemistry, Genetics and Molecular Biology | 3 | 20% |
| Immunology and Microbiology | 2 | 13% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 7% |
| Earth and Planetary Sciences | 1 | 7% |
| Other | 0 | 0% |
| Unknown | 2 | 13% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 August 2018.
All research outputs
#7,454,066
of 22,788,370 outputs
Outputs from Immunogenetics
#323
of 1,202 outputs
Outputs of similar age
#43,821
of 160,747 outputs
Outputs of similar age from Immunogenetics
#4
of 6 outputs
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