Title |
Current Concepts in the Treatment of Resectable Pancreatic Cancer
|
---|---|
Published in |
Current Oncology Reports, March 2018
|
DOI | 10.1007/s11912-018-0685-y |
Pubmed ID | |
Authors |
Marc T. Roth, Jordan D. Berlin |
Abstract |
The diagnosis of pancreatic cancer carries with it a high mortality rate. Despite advances in the field, this has remained relatively unchanged over the last few decades. Current options for the treatment of resectable pancreatic ductal adenocarcinoma will be reviewed here in conjunction with the historical data that support them. We will focus on updates in treatment guidelines and ongoing clinical trials of interest. For localized disease, standard of care includes resection followed by adjuvant chemotherapy ± chemoradiation. Recently, a report was published supporting the use of doublet therapy with gemcitabine and capecitabine (as opposed to gemcitabine monotherapy), which prompted a practice-changing update to major treatment guidelines. Multiple trials using neoadjuvant treatment, novel therapies, and different forms of radiation are ongoing. Although pancreatic cancer is an active area of research, outcomes remain dismal. Clinical trials will need to be more robust and innovative to drastically improve survival statistics. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 27% |
Brazil | 1 | 9% |
United Kingdom | 1 | 9% |
Unknown | 6 | 55% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 5 | 45% |
Practitioners (doctors, other healthcare professionals) | 3 | 27% |
Members of the public | 3 | 27% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 44 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 7 | 16% |
Student > Bachelor | 7 | 16% |
Other | 5 | 11% |
Researcher | 4 | 9% |
Student > Doctoral Student | 3 | 7% |
Other | 7 | 16% |
Unknown | 11 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 19 | 43% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 9% |
Agricultural and Biological Sciences | 4 | 9% |
Biochemistry, Genetics and Molecular Biology | 3 | 7% |
Immunology and Microbiology | 1 | 2% |
Other | 1 | 2% |
Unknown | 12 | 27% |