| Title |
Frequent expression loss of Inter-alpha-trypsin inhibitor heavy chain (ITIH) genes in multiple human solid tumors: A systematic expression analysis
|
|---|---|
| Published in |
BMC Cancer, January 2008
|
| DOI | 10.1186/1471-2407-8-25 |
| Pubmed ID | |
| Authors |
Alexander Hamm, Juergen Veeck, Nuran Bektas, Peter J Wild, Arndt Hartmann, Uwe Heindrichs, Glen Kristiansen, Tamra Werbowetski-Ogilvie, Rolando Del Maestro, Ruth Knuechel, Edgar Dahl |
| Abstract |
The inter-alpha-trypsin inhibitors (ITI) are a family of plasma protease inhibitors, assembled from a light chain - bikunin, encoded by AMBP - and five homologous heavy chains (encoded by ITIH1, ITIH2, ITIH3, ITIH4, and ITIH5), contributing to extracellular matrix stability by covalent linkage to hyaluronan. So far, ITIH molecules have been shown to play a particularly important role in inflammation and carcinogenesis. |
Mendeley readers
The data shown below were compiled from readership statistics for 131 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Italy | 1 | <1% |
| United Kingdom | 1 | <1% |
| Egypt | 1 | <1% |
| Belgium | 1 | <1% |
| Russia | 1 | <1% |
| Japan | 1 | <1% |
| Unknown | 125 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 28 | 21% |
| Student > Master | 19 | 15% |
| Student > Ph. D. Student | 17 | 13% |
| Student > Bachelor | 15 | 11% |
| Student > Postgraduate | 11 | 8% |
| Other | 22 | 17% |
| Unknown | 19 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 34 | 26% |
| Agricultural and Biological Sciences | 31 | 24% |
| Medicine and Dentistry | 30 | 23% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 2% |
| Nursing and Health Professions | 2 | 2% |
| Other | 8 | 6% |
| Unknown | 24 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 July 2018.
All research outputs
#7,454,066
of 22,788,370 outputs
Outputs from BMC Cancer
#2,059
of 8,290 outputs
Outputs of similar age
#42,717
of 156,135 outputs
Outputs of similar age from BMC Cancer
#4
of 11 outputs
Altmetric has tracked 22,788,370 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,290 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 68% of its peers.
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We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.