| Title |
TUCAN/CARDINAL/CARD8 and apoptosis resistance in non-small cell lung cancer cells
|
|---|---|
| Published in |
BMC Cancer, June 2006
|
| DOI | 10.1186/1471-2407-6-166 |
| Pubmed ID | |
| Authors |
Agnieszka Checinska, Giuseppe Giaccone, Bas SJ Hoogeland, Carlos G Ferreira, Jose A Rodriguez, Frank AE Kruyt |
| Abstract |
Activation of caspase-9 in response to treatment with cytotoxic drugs is inhibited in NSCLC cells, which may contribute to the clinical resistance to chemotherapy shown in this type of tumor. The aim of the present study was to investigate the mechanism of caspase-9 inhibition, with a focus on a possible role of TUCAN as caspase-9 inhibitor and a determinant of chemosensitivity in NSCLC cells. |
Mendeley readers
The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 2 | 12% |
| Netherlands | 1 | 6% |
| Unknown | 14 | 82% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 4 | 24% |
| Professor | 2 | 12% |
| Professor > Associate Professor | 2 | 12% |
| Student > Master | 2 | 12% |
| Student > Ph. D. Student | 2 | 12% |
| Other | 3 | 18% |
| Unknown | 2 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 5 | 29% |
| Medicine and Dentistry | 3 | 18% |
| Biochemistry, Genetics and Molecular Biology | 2 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 12% |
| Physics and Astronomy | 1 | 6% |
| Other | 1 | 6% |
| Unknown | 3 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 January 2008.
All research outputs
#7,454,066
of 22,788,370 outputs
Outputs from BMC Cancer
#2,059
of 8,290 outputs
Outputs of similar age
#22,442
of 63,924 outputs
Outputs of similar age from BMC Cancer
#5
of 17 outputs
Altmetric has tracked 22,788,370 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,290 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 63,924 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.