Title |
Angiotensin-Converting Enzyme Inhibitors vs. Angiotensin Receptor Blockers for the Treatment of Hypertension in Adults With Type 2 Diabetes: Why We Favour Angiotensin Receptor Blockers
|
---|---|
Published in |
Canadian Journal of Diabetes, December 2017
|
DOI | 10.1016/j.jcjd.2017.11.006 |
Pubmed ID | |
Authors |
Thomas A. Mavrakanas, Mark L. Lipman |
Abstract |
Cardiovascular disease is the principal cause of morbidity and mortality in patients with diabetes mellitus. The incidence or progression of kidney disease is also common in these patients. Several clinical trials have established the efficacy of angiotensin receptor blockers for the prevention of adverse cardiovascular and renal outcomes in this population and are summarized in this review article. Head-to-head comparison of angiotensin receptor blockers with angiotensin-converting enzyme inhibitors has shown similar cardioprotective and renoprotective properties of both medication classes. However, angiotensin receptor blockers have an improved safety profile with fewer episodes of cough and angioedema and may be the agent of choice in patients with diabetes and hypertension. Novel therapeutic strategies, such as those that include a mineralocorticoid receptor blocker or a selective sodium-glucose cotransporter type 2 inhibitor, may further protect patients with diabetes from cardiovascular and renal complications. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 47 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 11 | 23% |
Student > Master | 7 | 15% |
Student > Doctoral Student | 3 | 6% |
Researcher | 2 | 4% |
Student > Postgraduate | 2 | 4% |
Other | 7 | 15% |
Unknown | 15 | 32% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 13 | 28% |
Pharmacology, Toxicology and Pharmaceutical Science | 7 | 15% |
Nursing and Health Professions | 2 | 4% |
Immunology and Microbiology | 2 | 4% |
Biochemistry, Genetics and Molecular Biology | 2 | 4% |
Other | 4 | 9% |
Unknown | 17 | 36% |