| Title |
Impact of intravascular thrombosis on failure of radial arterial catheters in critically ill patients: a nested case-control study
|
|---|---|
| Published in |
Intensive Care Medicine, April 2018
|
| DOI | 10.1007/s00134-018-5149-1 |
| Pubmed ID | |
| Authors |
Yvan Fleury, Diego Arroyo, Caroline Couchepin, Helia Robert-Ebadi, Marc Righini, Johannes A. Lobrinus, Bara Ricou, Nathalie Delieuvin Schmitt, Angèle Gayet-Ageron |
| Abstract |
The patency of arterial catheters is essential for reliable invasive blood pressure monitoring. We sought to determine whether radial catheter failures were associated with intravascular thrombosis in critically ill adult patients. This unmatched case-control study was conducted within a prospective cohort of patients admitted to an intensive care unit. The arterial catheter failure was the main outcome, which identified cases. Controls were patients with patent catheter until removal or 28 days of follow-up. The prevalence of intravascular thrombosis in cases and controls was determined by ultrasonography of the cannulated radial artery. Assessors were blinded to clinical findings. Failing catheters were removed and examined microscopically. Catheter failures occurred in 25.5% of 200 patients during 584 catheter-days (incidence rate, 87/1000 catheter-days). The median patency duration was 13.1 days. An intravascular thrombosis located in front of the catheter tip was diagnosed in 42 of 50 cases (84.0%) and 24 of 139 controls (17.3%). In multivariable logistic regression analysis, the probability of catheter failure was higher in patients with intravascular thrombosis [odds ratio (OR), 36.52; 95% confidence interval (CI), 12.86-103.74] and females (OR, 3.45; 95% CI 1.32-9.05), increased proportionally to arterial blood sampling frequency (OR, 1.20; 95% CI 1.04-1.38), and decreased in thrombocytopenia (OR, 0.28; 95% CI 0.10-0.78). After removal, 15.7% of failing catheters had some luminal fibrin deposits, but none were occluded. Most failing radial arterial catheters had no luminal obstruction, but were associated with an intravascular thrombosis. Among predictive factors, arterial blood sampling frequency is the most susceptible to intervention. |
X Demographics
The data shown below were collected from the profiles of 69 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 12 | 17% |
| Spain | 5 | 7% |
| United States | 4 | 6% |
| France | 4 | 6% |
| Colombia | 3 | 4% |
| Brazil | 3 | 4% |
| Italy | 3 | 4% |
| Australia | 2 | 3% |
| Qatar | 2 | 3% |
| Other | 10 | 14% |
| Unknown | 21 | 30% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 52 | 75% |
| Practitioners (doctors, other healthcare professionals) | 10 | 14% |
| Scientists | 6 | 9% |
| Science communicators (journalists, bloggers, editors) | 1 | 1% |
Mendeley readers
The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 36 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 7 | 19% |
| Other | 6 | 17% |
| Researcher | 4 | 11% |
| Professor > Associate Professor | 3 | 8% |
| Student > Doctoral Student | 2 | 6% |
| Other | 5 | 14% |
| Unknown | 9 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 13 | 36% |
| Nursing and Health Professions | 9 | 25% |
| Agricultural and Biological Sciences | 1 | 3% |
| Business, Management and Accounting | 1 | 3% |
| Unknown | 12 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 49. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 May 2018.
All research outputs
#868,285
of 25,468,708 outputs
Outputs from Intensive Care Medicine
#818
of 5,424 outputs
Outputs of similar age
#19,440
of 342,942 outputs
Outputs of similar age from Intensive Care Medicine
#28
of 116 outputs
Altmetric has tracked 25,468,708 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,424 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 29.6. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 342,942 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 116 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.