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Association and insulin regulated translocation of hormone-sensitive lipase with PTRF

Overview of attention for article published in Biochemical & Biophysical Research Communications, September 2006
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Title
Association and insulin regulated translocation of hormone-sensitive lipase with PTRF
Published in
Biochemical & Biophysical Research Communications, September 2006
DOI 10.1016/j.bbrc.2006.09.094
Pubmed ID
Authors

Nabila Aboulaich, Unn Örtegren, Alexander V. Vener, Peter Strålfors

Abstract

Polymerase I and transcript release factor (PTRF) is in human adipocytes mainly localized at the plasma membrane. This localization was under control of insulin, which translocated PTRF to the cytosol and nucleus, indicating a novel role for PTRF in insulin transcriptional control. In the plasma membrane PTRF was specifically bound to a triacylglycerol-metabolizing subclass of caveolae containing hormone-sensitive lipase (HSL). In response to insulin PTRF was translocated to the cytosol in parallel with HSL. PTRF and HSL were quantitatively immunoprecipitated from the cytosol by antibodies against either PTRF or HSL. The findings indicate also a novel extranuclear function for PTRF in the control of lipolysis.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 8%
Spain 1 4%
Unknown 22 88%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 32%
Student > Ph. D. Student 7 28%
Professor 2 8%
Other 2 8%
Student > Master 2 8%
Other 2 8%
Unknown 2 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 44%
Biochemistry, Genetics and Molecular Biology 4 16%
Medicine and Dentistry 4 16%
Engineering 1 4%
Unknown 5 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 July 2018.
All research outputs
#8,571,053
of 25,457,858 outputs
Outputs from Biochemical & Biophysical Research Communications
#7,639
of 26,666 outputs
Outputs of similar age
#30,477
of 87,903 outputs
Outputs of similar age from Biochemical & Biophysical Research Communications
#59
of 164 outputs
Altmetric has tracked 25,457,858 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 26,666 research outputs from this source. They receive a mean Attention Score of 4.5. This one is in the 28th percentile – i.e., 28% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 87,903 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 164 others from the same source and published within six weeks on either side of this one. This one is in the 6th percentile – i.e., 6% of its contemporaries scored the same or lower than it.