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Mendeley readers
Attention Score in Context
| Title |
Three-Color FISH Analysis of TMPRSS2/ERG Fusions in Prostate Cancer Indicates That Genomic Microdeletion of Chromosome 21 Is Associated with Rearrangement
|
|---|---|
| Published in |
Neoplasia, June 2006
|
| DOI | 10.1593/neo.06283 |
| Pubmed ID | |
| Authors |
Maisa Yoshimoto, Anthony M. Joshua, Susan Chilton-MacNeill, Jane Bayani, Shamini Selvarajah, Andrew J. Evans, Maria Zielenska, Jeremy A. Squire |
| Abstract |
The recent description of novel recurrent gene fusions in approximately 80% of prostate cancer (PCa) cases has generated increased interest in the search for new translocations in other epithelial cancers and emphasizes the importance of understanding the origins and biologic implications of these genomic rearrangements. Analysis of 15 PCa cases by reverse transcription-polymerase chain reaction was used to detect six ERG-related gene fusion transcripts with TMPRSS2. No TMPRSS2/ETV1 chimeric fusion was detected in this series. Three-color fluorescence in situ hybridization confirms that TMPRSS2/ERG fusion may be accompanied by a small hemizygous sequence deletion on chromosome 21 between ERG and TMPRSS2 genes. Analysis of genomic architecture in the region of genomic rearrangement suggests that tracts of microhomology could facilitate TMPRSS2/ERG fusion events. |
Mendeley readers
The data shown below were compiled from readership statistics for 62 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 2 | 3% |
| Norway | 1 | 2% |
| United Kingdom | 1 | 2% |
| Canada | 1 | 2% |
| United States | 1 | 2% |
| Unknown | 56 | 90% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 17 | 27% |
| Researcher | 11 | 18% |
| Student > Master | 6 | 10% |
| Student > Doctoral Student | 5 | 8% |
| Professor | 5 | 8% |
| Other | 13 | 21% |
| Unknown | 5 | 8% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 20 | 32% |
| Medicine and Dentistry | 16 | 26% |
| Biochemistry, Genetics and Molecular Biology | 8 | 13% |
| Computer Science | 2 | 3% |
| Business, Management and Accounting | 1 | 2% |
| Other | 5 | 8% |
| Unknown | 10 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 July 2020.
All research outputs
#3,798,945
of 25,374,917 outputs
Outputs from Neoplasia
#121
of 1,368 outputs
Outputs of similar age
#8,886
of 86,561 outputs
Outputs of similar age from Neoplasia
#1
of 12 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,368 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 86,561 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.