| Title |
Membrane electroporation theories: a review
|
|---|---|
| Published in |
Medical & Biological Engineering & Computing, February 2006
|
| DOI | 10.1007/s11517-005-0020-2 |
| Pubmed ID | |
| Authors |
C. Chen, S.W. Smye, M.P. Robinson, J.A. Evans |
| Abstract |
Electroporation, the transient increase in the permeability of cell membranes when exposed to a high electric field, is an established in vitro technique and is used to introduce DNA or other molecules into cells. When the trans-membrane voltage induced by an external electric field exceeds a certain threshold (normally 0.2-1 V), a rearrangement of the molecular structure of the membrane occurs, leading to pore formation in the membrane and a considerable increase in the cell membrane permeability to ions, molecules and even macromolecules. This phenomenon is, potentially, the basis for many in vivo applications such as electrochemotherapy and gene therapy, but still lacks a comprehensive theoretical basis. This article reviews the state of current electroporation theories and briefly considers current and potential applications in biology and medicine. |
Mendeley readers
The data shown below were compiled from readership statistics for 408 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | <1% |
| France | 3 | <1% |
| Germany | 2 | <1% |
| Switzerland | 2 | <1% |
| Japan | 2 | <1% |
| Malaysia | 1 | <1% |
| Iran, Islamic Republic of | 1 | <1% |
| Brazil | 1 | <1% |
| United Kingdom | 1 | <1% |
| Other | 1 | <1% |
| Unknown | 391 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 106 | 26% |
| Researcher | 71 | 17% |
| Student > Bachelor | 56 | 14% |
| Student > Master | 52 | 13% |
| Student > Doctoral Student | 17 | 4% |
| Other | 45 | 11% |
| Unknown | 61 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Engineering | 90 | 22% |
| Agricultural and Biological Sciences | 85 | 21% |
| Biochemistry, Genetics and Molecular Biology | 39 | 10% |
| Physics and Astronomy | 25 | 6% |
| Chemistry | 22 | 5% |
| Other | 59 | 14% |
| Unknown | 88 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 July 2023.
All research outputs
#3,798,287
of 25,371,288 outputs
Outputs from Medical & Biological Engineering & Computing
#57
of 2,053 outputs
Outputs of similar age
#13,069
of 170,237 outputs
Outputs of similar age from Medical & Biological Engineering & Computing
#1
of 8 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,053 research outputs from this source. They receive a mean Attention Score of 3.8. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 170,237 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them