| Title |
The mammalian Nm23/NDPK family: from metastasis control to cilia movement
|
|---|---|
| Published in |
Molecular and Cellular Biochemistry, April 2009
|
| DOI | 10.1007/s11010-009-0120-7 |
| Pubmed ID | |
| Authors |
Mathieu Boissan, Sandrine Dabernat, Evelyne Peuchant, Uwe Schlattner, Ioan Lascu, Marie-Lise Lacombe |
| Abstract |
Nucleoside diphosphate kinases (NDPK) are encoded by the NME genes, also called NM23. They catalyze the transfer of gamma-phosphate from nucleoside triphosphates to nucleoside diphosphates by a ping-pong mechanism involving the formation of a high energy phospho-histidine intermediate [1, 2]. Besides their known functions in the control of intracellular nucleotide homeostasis, they are involved in multiple physiological and pathological cellular processes such as differentiation, development, metastastic dissemination or cilia functions. Over the past 15 years, ten human genes have been discovered encoding partial, full length, and/or tandemly repeated Nm23/NDPK domains, with or without N-or C-terminal extensions and/or additional domains. These genes encode proteins exhibiting different functions at various tissular and subcellular localizations. Most of these genes appear late in evolution with the emergence of the vertebrate lineage. This review summarizes the present knowledge on these multitalented proteins. |
Mendeley readers
The data shown below were compiled from readership statistics for 92 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 6 | 7% |
| France | 1 | 1% |
| Hungary | 1 | 1% |
| New Zealand | 1 | 1% |
| Ireland | 1 | 1% |
| Unknown | 82 | 89% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 22 | 24% |
| Researcher | 20 | 22% |
| Student > Master | 12 | 13% |
| Student > Bachelor | 8 | 9% |
| Student > Doctoral Student | 6 | 7% |
| Other | 12 | 13% |
| Unknown | 12 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 35 | 38% |
| Biochemistry, Genetics and Molecular Biology | 28 | 30% |
| Medicine and Dentistry | 6 | 7% |
| Engineering | 3 | 3% |
| Neuroscience | 2 | 2% |
| Other | 4 | 4% |
| Unknown | 14 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 July 2023.
All research outputs
#3,813,264
of 24,129,125 outputs
Outputs from Molecular and Cellular Biochemistry
#119
of 2,415 outputs
Outputs of similar age
#11,950
of 96,397 outputs
Outputs of similar age from Molecular and Cellular Biochemistry
#1
of 13 outputs
Altmetric has tracked 24,129,125 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,415 research outputs from this source. They receive a mean Attention Score of 3.9. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 96,397 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.