| Title |
The neuroligin and neurexin families: from structure to function at the synapse
|
|---|---|
| Published in |
Cellular and Molecular Life Sciences, June 2006
|
| DOI | 10.1007/s00018-006-6061-3 |
| Pubmed ID | |
| Authors |
M-F. Lisé, A. El-Husseini |
| Abstract |
Proper brain connectivity and neuronal transmission rely on the accurate assembly of neurotransmitter receptors, cell adhesion molecules and several other scaffolding and signaling proteins at synapses. Several new exciting findings point to an important role for the neuroligin family of adhesion molecules in synapse development and function. In this review, we summarize current knowledge of the structure of neuroligins and neurexins, their potential binding partners at the synapse. We also discuss their potential involvement in several aspects of synapse development, including induction, specificity and stabilization. The implication of neuroligins in cognitive disorders such as autism and mental retardation is also discussed. |
Mendeley readers
The data shown below were compiled from readership statistics for 265 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 6 | 2% |
| United Kingdom | 2 | <1% |
| Brazil | 1 | <1% |
| Israel | 1 | <1% |
| Netherlands | 1 | <1% |
| Georgia | 1 | <1% |
| Germany | 1 | <1% |
| Japan | 1 | <1% |
| Denmark | 1 | <1% |
| Other | 0 | 0% |
| Unknown | 250 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 56 | 21% |
| Researcher | 46 | 17% |
| Student > Bachelor | 44 | 17% |
| Student > Master | 33 | 12% |
| Professor > Associate Professor | 18 | 7% |
| Other | 36 | 14% |
| Unknown | 32 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 110 | 42% |
| Neuroscience | 52 | 20% |
| Biochemistry, Genetics and Molecular Biology | 20 | 8% |
| Medicine and Dentistry | 20 | 8% |
| Psychology | 9 | 3% |
| Other | 16 | 6% |
| Unknown | 38 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 April 2024.
All research outputs
#7,845,540
of 23,794,258 outputs
Outputs from Cellular and Molecular Life Sciences
#1,655
of 4,151 outputs
Outputs of similar age
#23,141
of 65,149 outputs
Outputs of similar age from Cellular and Molecular Life Sciences
#20
of 36 outputs
Altmetric has tracked 23,794,258 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,151 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 65,149 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 36 others from the same source and published within six weeks on either side of this one. This one is in the 2nd percentile – i.e., 2% of its contemporaries scored the same or lower than it.