| Title |
Polyunsaturated fatty acid metabolism in prostate cancer
|
|---|---|
| Published in |
Cancer and Metastasis Reviews, October 2011
|
| DOI | 10.1007/s10555-011-9299-7 |
| Pubmed ID | |
| Authors |
Isabelle M. Berquin, Iris J. Edwards, Steven J. Kridel, Yong Q. Chen |
| Abstract |
Polyunsaturated fatty acids (PUFA) play important roles in the normal physiology and in pathological states including inflammation and cancer. While much is known about the biosynthesis and biological activities of eicosanoids derived from ω6 PUFA, our understanding of the corresponding ω3 series lipid mediators is still rudimentary. The purpose of this review is not to offer a comprehensive summary of the literature on fatty acids in prostate cancer but rather to highlight some of the areas where key questions remain to be addressed. These include substrate preference and polymorphic variants of enzymes involved in the metabolism of PUFA, the relationship between de novo lipid synthesis and dietary lipid metabolism pathways, the contribution of cyclooxygenases and lipoxygenases as well as terminal synthases and prostanoid receptors in prostate cancer, and the potential role of PUFA in angiogenesis and cell surface receptor signaling. |
Mendeley readers
The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 1% |
| Unknown | 85 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 16 | 19% |
| Student > Ph. D. Student | 14 | 16% |
| Researcher | 13 | 15% |
| Student > Doctoral Student | 7 | 8% |
| Student > Bachelor | 6 | 7% |
| Other | 17 | 20% |
| Unknown | 13 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 22 | 26% |
| Biochemistry, Genetics and Molecular Biology | 18 | 21% |
| Medicine and Dentistry | 10 | 12% |
| Engineering | 4 | 5% |
| Chemistry | 3 | 3% |
| Other | 10 | 12% |
| Unknown | 19 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 February 2015.
All research outputs
#7,454,298
of 22,789,076 outputs
Outputs from Cancer and Metastasis Reviews
#286
of 807 outputs
Outputs of similar age
#46,841
of 140,148 outputs
Outputs of similar age from Cancer and Metastasis Reviews
#8
of 19 outputs
Altmetric has tracked 22,789,076 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 807 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
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