Title |
Approaches for Neural Tissue Regeneration
|
---|---|
Published in |
Stem Cell Reviews and Reports, October 2013
|
DOI | 10.1007/s12015-013-9474-z |
Pubmed ID | |
Authors |
Loïc Binan, Abdellah Ajji, Gregory De Crescenzo, Mario Jolicoeur |
Abstract |
There is currently no treatment for neurodegenerative diseases such as Parkinson's or Alzheimer's diseases. While spinal cord injury has no treatment either, nerve injuries are being treated with autologous grafts, a procedure that in turn translates into a loss of function in the donor area. The development of therapies for these pathologies has become urgent as population keeps on ageing. A promising direction of investigation is the use of regenerative techniques to re-grow healthy and functional tissue in the injured area. In this review article, various approaches currently investigated to promote neural regeneration are covered. Those include approaches based on (and many times combining) stem cell therapy, scaffolds made of hydrogel, electrospun fibers and conductive materials as well as the use of soluble or non-diffusible growth factors. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | <1% |
United States | 1 | <1% |
Unknown | 100 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 16 | 16% |
Student > Bachelor | 16 | 16% |
Researcher | 12 | 12% |
Student > Ph. D. Student | 11 | 11% |
Student > Doctoral Student | 6 | 6% |
Other | 14 | 14% |
Unknown | 27 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 24 | 24% |
Engineering | 14 | 14% |
Medicine and Dentistry | 10 | 10% |
Biochemistry, Genetics and Molecular Biology | 5 | 5% |
Neuroscience | 4 | 4% |
Other | 17 | 17% |
Unknown | 28 | 27% |