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PRMT6 diminishes HIV-1 Rev binding to and export of viral RNA

Overview of attention for article published in Retrovirology, December 2006
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2 Wikipedia pages

Citations

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54 Dimensions

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mendeley
48 Mendeley
Title
PRMT6 diminishes HIV-1 Rev binding to and export of viral RNA
Published in
Retrovirology, December 2006
DOI 10.1186/1742-4690-3-93
Pubmed ID
Authors

Cédric F Invernizzi, Baode Xie, Stéphane Richard, Mark A Wainberg

Abstract

The HIV-1 Rev protein mediates nuclear export of unspliced and partially spliced viral RNA through interaction with the Rev response element (RRE) by means of an arginine rich motif that is similar to the one found in Tat. Since Tat is known to be asymmetrically arginine dimethylated by protein arginine methyltransferase 6 (PRMT6) in its arginine rich motif, we investigated whether the Rev protein could act as a substrate for this enzyme.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
France 1 2%
Canada 1 2%
Unknown 45 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 31%
Researcher 8 17%
Student > Master 7 15%
Student > Bachelor 3 6%
Student > Doctoral Student 3 6%
Other 7 15%
Unknown 5 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 21 44%
Medicine and Dentistry 6 13%
Biochemistry, Genetics and Molecular Biology 5 10%
Immunology and Microbiology 4 8%
Earth and Planetary Sciences 2 4%
Other 4 8%
Unknown 6 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 August 2017.
All research outputs
#7,454,298
of 22,789,076 outputs
Outputs from Retrovirology
#408
of 1,106 outputs
Outputs of similar age
#41,874
of 156,208 outputs
Outputs of similar age from Retrovirology
#16
of 28 outputs
Altmetric has tracked 22,789,076 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,106 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has gotten more attention than average, scoring higher than 51% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 156,208 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.