Title |
Antibacterial potential of secondary metabolites produced by Aspergillus sp., an endophyte of Mitrephora wangii
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Published in |
Archives of Microbiology, April 2018
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DOI | 10.1007/s00203-018-1511-5 |
Pubmed ID | |
Authors |
Sakon Monggoot, Tanakrit Pichaitam, Chutima Tanapichatsakul, Patcharee Pripdeevech |
Abstract |
Mitrephora wangii, an ethnomedicinal plant, has been used as a natural antibiotic and immunity booster in Thailand. A total of 22 fungi were isolated from M. wangii flowers. The fungal isolates were categorized into six genera including Agrocybe, Aspergillus, Colletotrichum, Nigrospora, Puccinia and Ustilago. Most extracts exhibited antibacterial activity against at least one of the test bacteria. Aspergillus sp. MFLUCC16-0845 was identified as the most bioactive fungus. Chemical composition of Aspergillus sp. MFLUCC16-0845 investigated using gas chromatography-mass spectrometry indicated that the major antibacterial compound was β-thujaplicin. Moreover, the newly isolated Aspergillus sp. MFLUCC16-0845 could be exploited as a potential source of bioactive compounds and plant defense activators. In addition, it is the first time that strain of Aspergillus sp. isolated and cultured from M. wangii flowers could produce β-thujaplicin at high yield with strong antimicrobial spectrum, which may lead to wide utilization in producing cosmetics and clinical products. |
X Demographics
Geographical breakdown
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
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Unknown | 32 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 6 | 19% |
Student > Bachelor | 4 | 13% |
Student > Master | 3 | 9% |
Student > Postgraduate | 3 | 9% |
Researcher | 2 | 6% |
Other | 2 | 6% |
Unknown | 12 | 38% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 6 | 19% |
Agricultural and Biological Sciences | 5 | 16% |
Medicine and Dentistry | 3 | 9% |
Environmental Science | 2 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
Other | 2 | 6% |
Unknown | 13 | 41% |