Title |
Use of TaqMan Array Cards to Screen Outbreak Specimens for Causes of Febrile Illness in Tanzania.
|
---|---|
Published in |
The American Journal of Tropical Medicine and Hygiene, March 2018
|
DOI | 10.4269/ajtmh.18-0071 |
Pubmed ID | |
Authors |
Ahmed Abade, Rachel B Eidex, Athanasia Maro, Jean Gratz, Jie Liu, Ireen Kiwelu, Buliga Mujaga, Maria E Kelly, Blandina T Mmbaga, James J Gibson, Fausta Mosha, Eric R Houpt |
Abstract |
We describe the deployment of a custom-designed molecular diagnostic TaqMan Array Card (TAC) to screen for 31 bacterial, protozoal, and viral etiologies in blood from outbreaks of acute febrile illness in Tanzania during 2015-2017. On outbreaks notified to the Tanzanian Ministry of Health, epidemiologists were dispatched and specimens were collected, transported to a central national laboratory, and tested by TAC within 2 days. This algorithm streamlined investigation, diagnosed a typhoid outbreak, and excluded dozens of other etiologies. This method is usable in-country and may be incorporated into algorithms for diagnosing outbreaks. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 29 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 6 | 21% |
Other | 4 | 14% |
Student > Ph. D. Student | 4 | 14% |
Student > Postgraduate | 3 | 10% |
Student > Master | 3 | 10% |
Other | 1 | 3% |
Unknown | 8 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 4 | 14% |
Medicine and Dentistry | 4 | 14% |
Veterinary Science and Veterinary Medicine | 3 | 10% |
Immunology and Microbiology | 3 | 10% |
Biochemistry, Genetics and Molecular Biology | 2 | 7% |
Other | 3 | 10% |
Unknown | 10 | 34% |