Purine and Pyrimidine Metabolism in Man X

Table of Contents

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   Book Overview
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   Chapter 1 Purine and Pyrimidine Metabolism Between Millennia: What has been Accomplished, What has to be Done?
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   Chapter 2 Cell Type-Specific Differential Expression of Human PRPP Synthetase (PRPS) Genes
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   Chapter 3 Mutations in the Hypoxanthine-Guanine Phosphoribosyltransferase Gene in Spanish HPRT Deficient Families
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   Chapter 4 The Spectrum of Hypoxanthine-Guanine Phosphoribosyltransferase (HPRT) Deficiency
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   Chapter 5 Deletion in the Hypoxanthine Phosphoribosyltransferase Gene Caused by Alu-Alu Recombination in Two Japanese Patients With Lesch-Nyhan Syndrome
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   Chapter 6 Novel Genetic Mutations Responsible for the HPRT Deficiency and the Clinical Phenotypes in Japanese
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   Chapter 7 Adenoviruses encoding HPRT correct the biochemical abnormalities fully only in HPRT-deficient human cell lines: importance of species differences.
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   Chapter 8 Biochemical and immunological abnormalities in purine nucleoside phosphorylase deficient mice.
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    Chapter 9 Carrier Erythrocyte Entrapped Adenosine Deaminase Therapy in Adenosine Deaminase Deficiency
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    Chapter 10 ADA Activity and dATP Levels in Erythrocytes after Bone Marrow Transplantation
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    Chapter 11 Adenosine Deaminase-Deficient Mice: Models for the Study of Lymphocyte Development and Adenosine Signaling
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    Chapter 12 Inhibition of fetal thymic caspases abrogates the consequences of adenosine deaminase deficiency.
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    Chapter 13 Erythrocyte AMP Deaminase Deficiency in Japanese: A Compound Heterozygote Responsible for the Complete Deficiency
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    Chapter 14 Effect of Uridine Administration to a Patient with Adenylosuccinate Lyase Deficiency
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    Chapter 15 Adenylosuccinate Lyase Deficiency: From the Clinics to Molecular Biology
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    Chapter 16 Polymorphic Markers in the XDH Gene as Diagnostic Tools for Typing Classical Xanthinuria
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    Chapter 17 NAPDD Patients Exhibit Altered Electrophoretic Mobility of Cytosolic 5′ Nucleotidase
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    Chapter 18 Purines, Lactate and Myo-Inositol in CSF Might Reflect Excitotoxicity in Inherited Metabolic Disorders
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    Chapter 19 Cerebrospinal Fluid Purines, Pyrimidines, Organic Acids and Amino Acids in Neonatal Citrullinaemia
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    Chapter 20 Purine Nucleotide Catabolism in Rat Liver
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    Chapter 21 Further Refinement on the Engineering of Adenosine Phosphorylase from Purine Nucleoside Phosphorylase
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    Chapter 22 Human Guanine Deaminase: Cloning, Expression and Characterisation
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    Chapter 23 The human NUDT family of nucleotide hydrolases. Enzymes of diverse substrate specificity.
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    Chapter 24 Inhibitors of NTPDase: Key Players in the Metabolism of Extracellular Purines
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    Chapter 25 Apoptosis-Inducing Cleavage of Caspases by Trimidox, an Inhibitor of Ribonucleotide Reductase
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    Chapter 26 Increased Visceral Fat Accumulation in Patients with Primary Gout
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    Chapter 27 Serum Uric Acid Levels and Microalbuminuria in Mild Hypertensive Patients
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    Chapter 28 Guanosine-5′-Triphosphate Increases in Red Blood Cells of Heart Transplant Recipients Treated with Mycophenolate Mofetil
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    Chapter 29 Adenine incorporation in endothelial cells.
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    Chapter 30 TNF-alpha reduces the activity of ecto-5'-nucleotidase in human endothelial cells.
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    Chapter 31 Influence of age and heat stress on cardiac function and nucleotide levels.
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    Chapter 32 The role of 5'-deoxy-5'-methyl thioadenosine phosphorylase in cardiac adenosine breakdown and adenine production.
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    Chapter 33 The effect of adenosine metabolism inhibition and nucleotide precursor supply on adenosine production in human heart endothelial cells.
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    Chapter 34 Enhanced endogenous adenosine production and protection of the heart after transplantation.
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    Chapter 35 Role of Bovine Hemoglobin Enriched Cardioplegia in Myocardial Preservation
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    Chapter 36 Identification of the Potential Sensitive Urate/PAH Transporter from LLC-PK 1 Kidney Epithelial Cells
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    Chapter 37 Genomic Structure of Galectin-9 Gene
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    Chapter 38 Effect of Losartan and Furosemide on the Urinary Excretion of Oxypurinol and Uric Acid
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    Chapter 39 P2Y and P2X Purinoceptors are Respectively Implicated in Endothelium- Dependent Relaxation and Eedothelium Independent Contraction in Human Corpus Cavernosum
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    Chapter 40 ATP-Triggered Calcium Signals in Human Neutrophils
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    Chapter 41 The Role of A1/A3 Adenosine Receptor Activation in Reduction of Cardiomyocyte Injury Caused by Hypoxic Stress and in Induction of Apoptosis in Rat Cardiomyocyte Cultures
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    Chapter 42 Blockade of A 1 Receptors by Caffeine Induces C- fos , Zif -268 and ARC Expression in the Striatum Through Different Interactions with the Dopamine System
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    Chapter 43 Role of K ATP Channels in the Induction of Ischemic Tolerance by the ‘Adenosine Mechanism’ Neuronal Cultures
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    Chapter 44 Adenosine-Induced Caspase Activity in N1E-115 Cells
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    Chapter 45 Effect of Adenosine Receptor Agonists and Antagonists on Transport of Adenosine in Bovine Heart Microvascular Endothelial Cells
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    Chapter 46 Defects of Pyrimidine Degradation: Clinical, Molecular and Diagnostic Aspects
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    Chapter 47 Confirmation of the Enzyme Defect in the First Case of β-Ureidopropionase Deficiency
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    Chapter 48 Dihydropyrimidine Dehydrogenase (DPD) Deficiency: Novel Mutations in the DPD Gene
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    Chapter 49 Dihydropyrimidine Dehydrogenase Deficiency and 5-Fluorouracil Associated Toxicity
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    Chapter 50 Isoforms of human CTP synthetase.
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    Chapter 51 Polyclonal Antibodies Against the Ultrafast Multisubstrate Deoxyribonucleoside Kinase from Drosophila Melanogaster
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    Chapter 52 Inhibition and Localization of Human and Rat Dihydroorotate Dehydrogenase
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    Chapter 53 6-Mercaptopurine: Efficacy and Bone Marrow Toxicity in Childhood Acute Lymphoblastic Leukemia
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    Chapter 54 Recovery of SK-N-Be(2)C Cells from Treatmemt with Cyclopentenyl Cytosine
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    Chapter 55 Effect of Phosphorylation on Deoxycytidine Kinase Activity
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    Chapter 56 The Role of Deoxycytidine Kinase in Gemcitabine Cytotoxicity
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    Chapter 57 Thymidine Phosphorylase in Angiogenesis and Drug Resistance
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    Chapter 58 Secretion of thymidine by hybridoma cells.
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    Chapter 59 Thymidylate Synthase Inhibition Induces P53 Dependent and Independent Cell Death
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    Chapter 60 2-Chlorodeoxyadenosine (2-CDA) does not Change the Expression of Fas Antigen on Chronic Lymphocytic Leukaemia Cells
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    Chapter 61 Cyclopentenyl Cytosine Increases the Phosphorylation and Incorporation into DNA of Arabinofu-Ranosyl Cytosine in a Myeloid Leukemic Cell-Line
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    Chapter 62 Cyclopentenyl Cytosine Induces Apoptosis and Secondary Necrosis in a T-Lymphoblastic Leukemic Cell-Line
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    Chapter 63 Thiopurine Methyl Transferase: Activity and Genotyping in Patients with Acute Lymphoblastic Leukemia
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    Chapter 64 Hyperthermy Increase the Phosphorylation of Deoxycytidine in the Membrane Phospholipid Precursors and Decrease its Incorporation into DNA
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    Chapter 65 Purine Nucleotide Metabolism in Chronic Lymphocytic Leukemia Lymphocytes
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    Chapter 66 Inhibition of DNA Methylation by 5-Aza-2′-Deoxycytidine Correlates with Induction of K562 Cells Differentiation
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    Chapter 67 Evidence of Inhibition of DNA Methylation by Fludarabine
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    Chapter 68 The cytotoxic effect of purine riboside on COS-7 cells.
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    Chapter 69 Methylated and Non Methylated Thiopurine Nucleotide Ratio (ME6-MPN/6-TGN): Usefulness in the Monitoring of Azathioprine Therapy?
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    Chapter 70 Organ Preservation During Experimental Liver Transplantation
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    Chapter 71 Extraction and Purification of Ecto-5′-Nucleotidase from Human Lymphocytes
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    Chapter 72 HPLC/ESI Tandem-MS of Liquid Urine or Urine Soaked Filter-Paper Strips for the Detection of Thymine-Uraciluria and Dihydropyrimidinuria
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    Chapter 73 Screening for Purine and Pyrimidine Disorders Using Dried Urine Spots
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    Chapter 74 Determination of Methylated Purine Bases in Urine from Healthy Subjects
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    Chapter 75 Decrease in Urinary Uric Acid Concentrations after Urine Storage
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    Chapter 76 Mass Spectrometry for Analysis of Purine and Pyrimidine Compounds