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Mendeley readers
Attention Score in Context
| Title |
The oncogene and developmental regulator EVI1: Expression, biochemical properties, and biological functions
|
|---|---|
| Published in |
Gene, April 2007
|
| DOI | 10.1016/j.gene.2007.04.012 |
| Pubmed ID | |
| Authors |
Rotraud Wieser |
| Abstract |
The EVI1 gene codes for a zinc finger transcription factor with important roles both in normal development and in leukemogenesis. Transcriptional activation of this gene through chromosome rearrangements or other, yet to be identified mechanisms leads to particularly aggressive forms of human myeloid leukemia. In vitro as well as in animal model systems, EVI1 affected cellular proliferation, differentiation, and apoptosis in cell type specific ways. Retroviral integrations into the EVI1 locus provided cells with increased abilities to engraft, survive, and proliferate in bone marrow transplantation experiments. Experimental overexpression of EVI1 by itself was insufficient to cause leukemia in animal model systems, but it cooperated with other genes in this process. This review summarizes the currently available experimental evidence for the proposed biochemical and biological functions of this important oncogene. |
Mendeley readers
The data shown below were compiled from readership statistics for 99 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 2% |
| Netherlands | 1 | 1% |
| Australia | 1 | 1% |
| Austria | 1 | 1% |
| Japan | 1 | 1% |
| Czechia | 1 | 1% |
| Unknown | 92 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 25 | 25% |
| Researcher | 15 | 15% |
| Student > Master | 15 | 15% |
| Student > Bachelor | 10 | 10% |
| Other | 9 | 9% |
| Other | 18 | 18% |
| Unknown | 7 | 7% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 36 | 36% |
| Biochemistry, Genetics and Molecular Biology | 24 | 24% |
| Medicine and Dentistry | 18 | 18% |
| Chemistry | 3 | 3% |
| Immunology and Microbiology | 2 | 2% |
| Other | 7 | 7% |
| Unknown | 9 | 9% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 July 2017.
All research outputs
#3,907,044
of 26,017,215 outputs
Outputs from Gene
#564
of 11,031 outputs
Outputs of similar age
#10,625
of 91,572 outputs
Outputs of similar age from Gene
#4
of 39 outputs
Altmetric has tracked 26,017,215 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 11,031 research outputs from this source. They receive a mean Attention Score of 3.9. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 91,572 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 39 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.