↓ Skip to main content

Expression of human neuronal protein 22, a novel cytoskeleton-associated protein, was decreased in the anterior cingulate cortex of schizophrenia

Overview of attention for article published in Neuroscience Letters, April 2005
Altmetric Badge

Mentioned by

wikipedia
2 Wikipedia pages

Citations

dimensions_citation
22 Dimensions

Readers on

mendeley
25 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Expression of human neuronal protein 22, a novel cytoskeleton-associated protein, was decreased in the anterior cingulate cortex of schizophrenia
Published in
Neuroscience Letters, April 2005
DOI 10.1016/j.neulet.2004.12.079
Pubmed ID
Authors

Masayuki Ito, Iris Depaz, Peter Wilce, Toshimitsu Suzuki, Shin-ichi Niwa, Izuru Matsumoto

Abstract

Human neuronal protein 22 (hNP22) is a novel neuron-specific protein featuring numerous motifs previously described in cytoskeleton-associating and signaling proteins. Because previous studies have supported abnormalities in neuronal cytoarchitecture and/or development in the schizophrenia brain, we examined the expression of hNP22 in the anterior cingulate cortex, the hippocampus and the prefrontal cortex of schizophrenic and normal control postmortem brains using high-sensitive immunohistochemistry. Seven schizophrenic and seven age- and sex-matched control brains were examined. The ratio of hNP22-immunopositive cells/total cells was significantly reduced in layer V (p=.020) and layer VI (p=.022) of the anterior cingulate cortex of schizophrenic brain compared with controls. In contrast, there were no significant changes observed in the hippocampus and the prefrontal cortex. These results suggest that altered expression of hNP22 may be associated with modifications in neuronal cytoarchitecture leading to dysregulation of neural signal transduction in the anterior cingulate cortex of the schizophrenia brain.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 4%
Unknown 24 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 24%
Student > Bachelor 3 12%
Professor 3 12%
Student > Ph. D. Student 3 12%
Professor > Associate Professor 2 8%
Other 2 8%
Unknown 6 24%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 28%
Neuroscience 4 16%
Psychology 2 8%
Medicine and Dentistry 2 8%
Pharmacology, Toxicology and Pharmaceutical Science 1 4%
Other 0 0%
Unknown 9 36%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 July 2018.
All research outputs
#8,534,528
of 25,373,627 outputs
Outputs from Neuroscience Letters
#2,300
of 7,756 outputs
Outputs of similar age
#25,977
of 74,414 outputs
Outputs of similar age from Neuroscience Letters
#12
of 41 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,756 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 74,414 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 41 others from the same source and published within six weeks on either side of this one. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.