| Title |
Hepatitis B Virus (HBV) and Autoimmune Disease
|
|---|---|
| Published in |
Clinical Reviews in Allergy & Immunology, September 2007
|
| DOI | 10.1007/s12016-007-8013-6 |
| Pubmed ID | |
| Authors |
Ram Maya, M. Eric Gershwin, Yehuda Shoenfeld |
| Abstract |
The etiology and pathogenesis of autoimmune diseases have long been an enigmatic subject that have involved genetic and environmental factors. Recent intriguing data has contributed to the mechanisms involved, including the relationship of infectious agents and loss of tolerance. This loss of tolerance is illustrated by the data on the immune response to Hepatitis B virus such as the molecular mimicry between HBV antigens and self proteins, the generation of immune complexes between HBV antigens and antibodies, and apoptosis/tissue damage resulting in the exposure of intracellular antigens to the immune system. In this paper, we review the current database related to HBV infection and a variety of autoimmune conditions, including autoimmune hepatitis, systemic lupus erythematosus, aplastic anemia, antiphospholipid syndrome, polyarteritis nodosa, rheumatoid arthritis, type 1 diabetes, multiple sclerosis, thyroid disease and uveitis. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 17% |
| Australia | 1 | 17% |
| Unknown | 4 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 83% |
| Scientists | 1 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Colombia | 1 | 1% |
| Germany | 1 | 1% |
| United Kingdom | 1 | 1% |
| Japan | 1 | 1% |
| United States | 1 | 1% |
| Unknown | 81 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 12 | 14% |
| Researcher | 12 | 14% |
| Student > Bachelor | 10 | 12% |
| Other | 7 | 8% |
| Student > Master | 7 | 8% |
| Other | 18 | 21% |
| Unknown | 20 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 41 | 48% |
| Agricultural and Biological Sciences | 7 | 8% |
| Biochemistry, Genetics and Molecular Biology | 5 | 6% |
| Immunology and Microbiology | 4 | 5% |
| Neuroscience | 2 | 2% |
| Other | 6 | 7% |
| Unknown | 21 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 21. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 June 2021.
All research outputs
#1,639,944
of 23,975,976 outputs
Outputs from Clinical Reviews in Allergy & Immunology
#46
of 690 outputs
Outputs of similar age
#3,255
of 72,485 outputs
Outputs of similar age from Clinical Reviews in Allergy & Immunology
#1
of 14 outputs
Altmetric has tracked 23,975,976 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 690 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.8. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 72,485 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.