Title |
Comparative Efficiency of Proproten-100 during the Therapy of Patients with Alcoholism in the Stage of Therapeutic Remission
|
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Published in |
Bulletin of Experimental Biology and Medicine, January 2003
|
DOI | 10.1023/a:1024709014483 |
Pubmed ID | |
Authors |
N. A. Bokhan, A. F. Abolonin, E. N. Krylov, T. P. Vetlugina, S. A. Ivanova |
Abstract |
An open comparative clinical study evaluated the efficiency of Proproten-100 in reliving affective, somatovegetative, behavioral, and cognitive post-withdrawal disorders and manifestations of primary pathological alcohol addiction in patients with alcohol dependence in the stage of therapeutic remission. We compared the efficiency of Proproten-100 and standard symptomatic drugs. The preparation possessed anxiolytic, antidepressant, and vegetostabilizing properties, produced a moderate soporific effect, and had no sedative activity in patients with dysphoric depressions and psychopathic disorders. Proproten-100 was more effective during the therapy of patients with anxious and wistful depressions. Proproten-100 increased the contents of IgG and natural antibodies against S100 protein in the blood from patients. The preparation did not cause side effect or development of tolerance. Proproten-100 has psychotropic properties and holds much promise for long-term treatment of patients with alcohol dependence to reduce the incidence of recurrences. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 24 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 4 | 17% |
Researcher | 4 | 17% |
Student > Master | 3 | 13% |
Professor | 2 | 8% |
Student > Postgraduate | 2 | 8% |
Other | 6 | 25% |
Unknown | 3 | 13% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 9 | 38% |
Psychology | 8 | 33% |
Nursing and Health Professions | 2 | 8% |
Social Sciences | 1 | 4% |
Sports and Recreations | 1 | 4% |
Other | 0 | 0% |
Unknown | 3 | 13% |