Enzymology and Molecular Biology of Carbonyl Metabolism 4

Table of Contents

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   Book Overview
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   Chapter 1 Aldehyde Dehydrogenases — The 1992 Perspective
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   Chapter 2 Metabolic Role of Aldehyde Dehydrogenase
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   Chapter 3 Effects of Aldehyde Products of Lipid Peroxidation on the Activity of Aldehyde Metabolizing Enzymes in Hepatomas
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   Chapter 4 Metabolic Interactions of 4-Hydroxynonenal, Acetaldehyde and Glutathione in Isolated Liver Mitochondria
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   Chapter 5 Biological Role of Human Cytosolic Aldehyde Dehygrogenase 1: Hormonal Response, Retinal Oxidation and Implication in Testicular Feminization
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   Chapter 6 Human Cytosolic Aldehyde Dehydrogenase in Androgen Insensitivity Syndrome
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   Chapter 7 The use of Immortalized Mouse L1210/OAP Cells Established in Culture to Study the Major Class 1 Aldehyde Dehydrogenase-Catalyzed Oxidation of Aldehydes in Intact Cells
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   Chapter 8 Enhanced Transcription of the Cytosolic ALDH Gene in Cyclophosphamide Resistant Human Carcinoma Cells
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    Chapter 9 Attempts to Increase the Expression of Rat Liver Mitochondrial Aldehyde Dehydrogenase in E. coli by Altering the mRNA
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    Chapter 10 Preliminary Characterization of the Rat Class 3 Aldehyde Dehydrogenase Gene
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    Chapter 11 Human High-K m , Aldehyde Dehydrogenase (ALDH3): Molecular, Kinetic and Structural Features
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    Chapter 12 Overexpression or Polycyclic Aromatic Hydrocarbon-Mediated Induction of an Apparently Novel Class 3 Aldehyde Dehydrogenase in Human Breast Adenocarcinoma Cells and its Relationship to Oxazaphosphorine-Specific Acquired Resistance
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    Chapter 13 Tumor-Associated Aldehyde Dehydrogenase (ALDH3): Expression in Diffrent Human Tumor Cell Lines with and without Treatment with 3-Methylcholanthrene
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    Chapter 14 Sexual Differentiation in the Induction of the Class 3 Aldehyde Dehydrogenase
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    Chapter 15 Mouse Class 3 Aldehyde Dehydrogenases: Positive and Negative Regulation of Gene Expression
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    Chapter 17 Bovine Corneal Aldehyde Dehydrogenases: Evidence for Multiple Gene Products (ALDH3 and ALDHX)
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    Chapter 18 Carbonyl-metabolizing enzymes and their relatives recruited as structural proteins in the eye lens.
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    Chapter 19 Members of the ALDH Gene Family are Lens and Corneal Crystallins
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    Chapter 20 Retinoic Acid Synthesis in the Developing Retina
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    Chapter 21 Human Liver High Km Aldehyde Dehydrogenase (ALDH4): Properties and Structural Relationship to the Glutamic γ-Semialdehyde Dehydrogenase
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    Chapter 22 Effect of some compounds related to disulfiram on mitochondrial aldehyde dehydrogenase in vitro and in vivo.
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    Chapter 23 Photoaffinity Labeling of Aldehyde Dehydrogenase from Horse Liver by P 1 -N 6 -(4-Azidophenylethyl)adenosine-P 2 -[4-(3-Azidopyridinio)Butyl] Diphosphate
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    Chapter 24 Aldehyde Dehydrogenase: Aldehyde Dehydrogenation and Ester Hydrolysis
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    Chapter 25 Is the single site binding model for aldehyde dehydrogenase an oversimplification? The one-site, two-site debate revisited.
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    Chapter 26 Crystallization and Preliminary X-ray Analysis of Bovine Mitochondrial Aldehyde Dehydrogenase and Human Glutathione-Dependent Formaldehyde Dehydrogenase
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    Chapter 27 The Aldo-Keto Reductases: an Overview
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    Chapter 28 Location of an Essential Arginine Residue in the Primary Structure of Pig Aldose Reductase
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    Chapter 29 CYS 298 is Responsible for Reversible Thiol-Induced Variation in Aldose Reductase Activity
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    Chapter 30 Substrate Specificity of Reduced and Oxidized Forms of Human Aldose Reductase
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    Chapter 31 Kinetic Alteration of Human Aldose Reductase by Mutagenesis of Cysteine Residues
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    Chapter 32 Inhibition of Aldose Reductase By (2, 6-Dimethylphenylsulphonyl)Nitromethane: Possible Implications for the Nature of an Inhibitor Binding Site and A Cause of Biphasic Kinetics
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    Chapter 33 Sepiapterin Reductase and ALR2 (“Aldose Reductase”) from Bovine Brain
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    Chapter 34 Polymorphisms of the Aldose Reductase Locus (ALR2) and Susceptibility to Diabetic Microvascular Complications
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    Chapter 35 Polycyclic Aromatic Hydrocarbons and Phenolic Antioxidants do not Significantly Induce Carbonyl Reductase in Human Cell Lines
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    Chapter 36 The Purification and Properties of a Novel Carbonyl Reducing Enzyme from Mouse Liver Microsomes
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    Chapter 37 Properties and Stereoselectivity of Carbonyl Reductases Involved in the Ketone Reduction of Warfarin and Analogues
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    Chapter 38 Activation of Pulmonary Carbonyl Reductase by Aromatic Amines and Pyridine Ring-Containing Compounds
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    Chapter 39 Unique Dihydrodiol Specific Dehydrogenase of Bovine Liver: Inhibition Studies and Comparison with Aldo/Keto Reductase
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    Chapter 40 Carbonyl Reduction by 3α-HSD from Comamonas Testosteroni — New Properties and its Relationship to the SCAD Family
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    Chapter 41 Substrate Specificity of Alcohol Dehydrogenases
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    Chapter 42 The Influence of pH on the Substrate Specificity and Stereoselectivity of Alcohol Dehydrogenase from Horse Liver
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    Chapter 43 The Catalytic Specificity of Liver Alcohol Dehydrogenase: Vitamin A Alcohol and Vitamin A Aldehyde Activities
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    Chapter 44 A Synthetic Approach to Analysis of the Structural Zinc Site of Alcohol Dehydrogenase
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    Chapter 45 Kinetics of A Glycine for Arg-47 Human Alcohol Dehydrogenase Mutant Can be Explained by Lys-228 Recruitment into the Pyrophosphate Binding Site
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    Chapter 46 Site-Directed Mutagenesis of Mammalian Alcohol and Sorbitol Dehydrogenases Map Functional Differences within the Enzyme Family
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    Chapter 47 Horse Liver Alcohol Dehydrogenase — S — Isozyme: Confirmation of the Primary Structure by Protein Sequencing and Ion Spray Mass Spectrometry
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    Chapter 48 Mixed Substrate Experiments with Class III (χ) Alcohol Dehydrogenases from Human and Pig Liver and Stomach
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    Chapter 49 Glutathione-Dependent Formaldehyde Dehydrogenase/Class III Alcohol Dehydrogenase: Further Characterization of the Rat Liver Enzyme
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    Chapter 50 Class IV Alcohol Dehydrogenase: Structure and Function
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    Chapter 51 The Oxidation of Aldehydes by Horse Liver Alcohol Dehydrogenase
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    Chapter 52 Effect of Glycation Upon Activity of Liver Alcohol Dehydrogenase
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    Chapter 53 Kinetically Specific Spin-Label Substrates of Liver Alcohol Dehydrogenase and of Liver Aldehyde Dehydrogenase
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    Chapter 54 Fluorescence Studies of Ternary Complexes of Liver Alcohol Dehydrogenase
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    Chapter 55 Evolutionary Relationships of Branched Chain and Non-specific Alcohol and Aldehyde Dehydrogenases
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    Chapter 56 Enzyme and Isozyme Developments within the Medium-Chain Alcohol Dehydrogenase Family
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    Chapter 57 Tissue Distribution of Alcohol and Sorbitol Dehydrogenase mRNAs
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    Chapter 58 The Role of Alcohol and Aldehyde Dehydrogenases In Alcohol-Related Diseases: Clinical Studies of Molecular Markers
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    Chapter 59 Regulation of the Human Alcohol Dehydrogenase Genes ADH1 , ADH2 and ADH3 : Differences in Cis -Acting Sequences At CTF/NF-I Sites
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    Chapter 60 DNA Elements Mediating Retinoid and Thyroid Hormone Regulation of Alcohol Dehydrogenase Gene Expression
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    Chapter 61 Modulation of Hepatic and Renal Alcohol Dehydrogenase Activity and mRNA By Steroid Hormones in Vivo
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    Chapter 62 Alcohol- and Aldehyde-Dehydrogenase: Modulation By Biogenic Amine Metabolites, Neuropeptides and Psychoactive Agents
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    Chapter 63 Microbial Alcohol, Aldehyde and Formate Ester Oxidoreductases
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    Chapter 64 Carbonyl Metabolising Enzymes in Alkane-Grown Microorganisms