| Title |
Epigenetic control of the basal-like gene expression profile via Interleukin-6 in breast cancer cells
|
|---|---|
| Published in |
Molecular Cancer, November 2010
|
| DOI | 10.1186/1476-4598-9-300 |
| Pubmed ID | |
| Authors |
Laura D'Anello, Pasquale Sansone, Gianluca Storci, Valentina Mitrugno, Gabriele D'Uva, Pasquale Chieco, Massimiliano Bonafé |
| Abstract |
Basal-like carcinoma are aggressive breast cancers that frequently carry p53 inactivating mutations, lack estrogen receptor-α (ERα) and express the cancer stem cell markers CD133 and CD44. These tumors also over-express Interleukin 6 (IL-6), a pro-inflammatory cytokine that stimulates the growth of breast cancer stem/progenitor cells. |
Mendeley readers
The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Iran, Islamic Republic of | 1 | 2% |
| United Kingdom | 1 | 2% |
| Unknown | 61 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 17 | 27% |
| Student > Ph. D. Student | 8 | 13% |
| Professor > Associate Professor | 6 | 10% |
| Student > Bachelor | 5 | 8% |
| Professor | 5 | 8% |
| Other | 10 | 16% |
| Unknown | 12 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 16 | 25% |
| Agricultural and Biological Sciences | 16 | 25% |
| Biochemistry, Genetics and Molecular Biology | 10 | 16% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 5% |
| Immunology and Microbiology | 3 | 5% |
| Other | 3 | 5% |
| Unknown | 12 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 January 2019.
All research outputs
#2,279,780
of 22,789,566 outputs
Outputs from Molecular Cancer
#109
of 1,719 outputs
Outputs of similar age
#13,321
of 180,062 outputs
Outputs of similar age from Molecular Cancer
#4
of 23 outputs
Altmetric has tracked 22,789,566 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,719 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 180,062 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 82% of its contemporaries.