| Title |
Role of the Microbiome in Food Allergy
|
|---|---|
| Published in |
Current Allergy and Asthma Reports, April 2018
|
| DOI | 10.1007/s11882-018-0780-z |
| Pubmed ID | |
| Authors |
Hsi-en Ho, Supinda Bunyavanich |
| Abstract |
Resident microbial communities likely modify risk for allergic disorders, including food allergy. We review epidemiologic studies linking microbial exposures to food allergy risk and discuss the mechanisms by which the microbiome may modulate oral tolerance. We additionally address ongoing translational efforts in human microbiome studies. Epidemiologic studies and murine models support that altered microbial exposures and colonization in early life modify food allergy risk. Differential microbiota confer protection or susceptibility to food allergy by modulating the regulatory tone of the mucosal immune system. Recent efforts are focused on the identification of bacterial strains necessary for oral tolerance in human and microbial-based clinical trials. Early childhood appears to be critical for the colonization of a diverse microbiota necessary for the induction and maintenance of oral tolerance. Identification and functional evaluation of protective commensal microbes will inform strategies for the prevention and treatment of food allergy. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Scientists | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 130 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 130 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 18 | 14% |
| Student > Bachelor | 15 | 12% |
| Researcher | 14 | 11% |
| Student > Doctoral Student | 11 | 8% |
| Student > Ph. D. Student | 8 | 6% |
| Other | 16 | 12% |
| Unknown | 48 | 37% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 21 | 16% |
| Medicine and Dentistry | 19 | 15% |
| Biochemistry, Genetics and Molecular Biology | 17 | 13% |
| Immunology and Microbiology | 8 | 6% |
| Nursing and Health Professions | 6 | 5% |
| Other | 13 | 10% |
| Unknown | 46 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 March 2023.
All research outputs
#2,470,361
of 25,530,891 outputs
Outputs from Current Allergy and Asthma Reports
#97
of 860 outputs
Outputs of similar age
#50,606
of 343,780 outputs
Outputs of similar age from Current Allergy and Asthma Reports
#3
of 18 outputs
Altmetric has tracked 25,530,891 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 860 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.4. This one has done well, scoring higher than 88% of its peers.
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We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.