| Title |
In vivo imaging of saccular hydrops in humans reflects sensorineural hearing loss rather than Meniere’s disease symptoms
|
|---|---|
| Published in |
European Radiology, March 2018
|
| DOI | 10.1007/s00330-017-5260-7 |
| Pubmed ID | |
| Authors |
Arnaud Attyé, Michael Eliezer, Maud Medici, Irène Tropres, Georges Dumas, Alexandre Krainik, Sébastien Schmerber |
| Abstract |
A case-controlled imaging study demonstrated that saccular hydrops was specific to Meniere's disease (MD), but only present in a subset of patients. Here, we compared patients with definite MD, vertigo and sensorineural hearing loss (SNHL) to elucidate the relationship between saccular hydrops and extent of SNHL. In this prospective study, we performed 3D-FLAIR sequences between 4.5 and 5.5 h after contrast media injection in patients with MD (n=20), SNHL (n=20), vertigo (n=20) and 30 healthy subjects. Two radiologists independently graded saccular hydrops. ROC analysis was performed to determine the hearing loss threshold to differentiate patients with saccular hydrops. Saccular hydrops was found in 11 of 20 MD patients, 10 of 20 SNHL patients and in none of the vertigo patients and healthy subjects. In SNHL patients, 45 dB was the threshold above which there was a significant association with saccular hydrops, with sensitivity of 100 % and specificity of 90 %. In MD patients, 40 dB was the threshold above which there was a significant association with saccular hydrops, with sensitivity of 100 % and specificity of 44 %. Our results indicate saccular hydrops as a feature of worse than moderate SNHL rather than MD itself. • MRI helps clinicians to assess patients with isolated low-tone sensorineural hearing loss. • Saccular hydrops correlates with sensorineural hearing loss at levels above 40 dB. • Vertigo patients without sensorineural hearing loss do not have saccular hydrops. • Saccular hydrops is described in patients without clinical diagnosis of Meniere's disease. |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 58 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 58 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 9 | 16% |
| Student > Master | 7 | 12% |
| Student > Bachelor | 7 | 12% |
| Other | 5 | 9% |
| Student > Ph. D. Student | 3 | 5% |
| Other | 8 | 14% |
| Unknown | 19 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 23 | 40% |
| Neuroscience | 3 | 5% |
| Nursing and Health Professions | 2 | 3% |
| Engineering | 2 | 3% |
| Social Sciences | 1 | 2% |
| Other | 3 | 5% |
| Unknown | 24 | 41% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 April 2018.
All research outputs
#18,601,965
of 23,041,514 outputs
Outputs from European Radiology
#2,969
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Outputs of similar age
#258,190
of 332,419 outputs
Outputs of similar age from European Radiology
#56
of 83 outputs
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