| Title |
Latent Membrane Protein 1 as a molecular adjuvant for single-cycle lentiviral vaccines
|
|---|---|
| Published in |
Retrovirology, May 2011
|
| DOI | 10.1186/1742-4690-8-39 |
| Pubmed ID | |
| Authors |
Sachin Gupta, James M Termini, Liguo Niu, Saravana K Kanagavelu, Andrew R Rahmberg, Richard S Kornbluth, David T Evans, Geoffrey W Stone |
| Abstract |
Molecular adjuvants are a promising method to enhance virus-specific immune responses and protect against HIV-1 infection. Immune activation by ligands for receptors such as CD40 can induce dendritic cell activation and maturation. Here we explore the incorporation of two CD40 mimics, Epstein Barr Virus gene LMP1 or an LMP1-CD40 chimera, into a strain of SIV that was engineered to be limited to a single cycle of infection. |
Mendeley readers
The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 6% |
| Unknown | 17 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 5 | 28% |
| Professor | 3 | 17% |
| Student > Bachelor | 2 | 11% |
| Student > Master | 2 | 11% |
| Researcher | 1 | 6% |
| Other | 1 | 6% |
| Unknown | 4 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 6 | 33% |
| Immunology and Microbiology | 3 | 17% |
| Biochemistry, Genetics and Molecular Biology | 2 | 11% |
| Chemical Engineering | 1 | 6% |
| Environmental Science | 1 | 6% |
| Other | 2 | 11% |
| Unknown | 3 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 March 2019.
All research outputs
#3,272,447
of 22,789,566 outputs
Outputs from Retrovirology
#156
of 1,106 outputs
Outputs of similar age
#16,029
of 111,868 outputs
Outputs of similar age from Retrovirology
#3
of 13 outputs
Altmetric has tracked 22,789,566 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,106 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has done well, scoring higher than 85% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 111,868 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.