Title |
Osteoblast cell adhesion on a laser modified zirconia based bioceramic
|
---|---|
Published in |
Journal of Materials Science: Materials in Medicine, August 2005
|
DOI | 10.1007/s10856-005-2608-3 |
Pubmed ID | |
Authors |
L. Hao, J. Lawrence, K. S. Chian |
Abstract |
Due to their attractive mechanical properties, bioinert zirconia bioceramics are frequently used in the high load-bearing sites such as orthopaedic and dental implants, but they are chemically inert and do not naturally form a direct bond with bone and thus do not provide osseointegration. A CO2 laser was used to modify the surface properties with the aim to achieve osseointegration between bioinert zirconia and bone. The surface characterisation revealed that the surface roughness decreased and solidified microstructure occurred after laser treatment. Higher wettability characteristics generated by the CO2 laser treatment was primarily due to the enhancement of the surface energy, particularly the polar component, determined by microstructural changes. An in vitro test using human fetal osteoblast cells (hFOB) revealed that osteoblast cells adhere better on the laser treated sample than the untreated sample. The change in the wettability characteristics could be the main mechanism governing the osteoblast cell adhesion on the YPSZ. |
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Geographical breakdown
Country | Count | As % |
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Germany | 1 | <1% |
France | 1 | <1% |
Israel | 1 | <1% |
United Kingdom | 1 | <1% |
Spain | 1 | <1% |
Unknown | 96 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 24 | 24% |
Student > Master | 14 | 14% |
Student > Doctoral Student | 10 | 10% |
Researcher | 10 | 10% |
Professor > Associate Professor | 7 | 7% |
Other | 12 | 12% |
Unknown | 24 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Materials Science | 25 | 25% |
Medicine and Dentistry | 22 | 22% |
Engineering | 11 | 11% |
Chemistry | 3 | 3% |
Physics and Astronomy | 2 | 2% |
Other | 4 | 4% |
Unknown | 34 | 34% |