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Prions and Brain Diseases in Animals and Humans

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Table of Contents

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    Book Overview
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    Chapter 1 Introduction — Guide to the Talks
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    Chapter 2 Polymorphic Genotype Matching in Acquired Creutzfeldt-Jakob Disease: An Analysis of Donor/Recipient Case Pairs
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    Chapter 3 Human Prion Protein Gene Mutation at Codon 183 Associated with an Atypical Form of Prion Disease
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    Chapter 4 Fatal Familial Insomnia: A Human Model of Prion Disease
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    Chapter 5 Mechanisms of Phenotypic Heterogeneity in Human Prion Diseases
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    Chapter 6 Transgenic Mice with Neuron-Specific Expression of a Hamster Prion Protein Minigene Are Susceptible to Hamster Scrapie Agent
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    Chapter 7 The Use of Transgenic Mice in the Investigation of Transmissible Spongiform Encephalopathies
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    Chapter 8 Large-Scale Sequencing of Human, Mouse, and Sheep Prion Protein Genes
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    Chapter 9 Electron Microscopy in Prion Research: Tubulovesicular Structures Are Not Composed of Prion Protein (PrP) but They May Be Intimately Associated with PrP Amyloid Fibrils
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    Chapter 10 Familial Prion Diseases Modeled in Cell Culture
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    Chapter 11 Yeast Approach to Protein “Prionization”: SUP35-[PSI] System
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    Chapter 12 Prions of Yeast: Genetic Evidence that the Non-Mendelian Elements, [PSI] and [URE3] Are Altered Self-Replicating Forms of Sup35p and Ure2p, Respectively
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    Chapter 13 Early Clinical Detection of Brain Diseases in Animals
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    Chapter 14 Prion Biology and Diseases — Fatal Conformations of Proteins during a Journey from Heresy to Orthodoxy
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    Chapter 15 New Variant Creutzfeldt-Jakob Disease
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    Chapter 16 The Molecular Basis of Cellular Dysfunction in Prion Diseases
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    Chapter 17 Presenilin Proteins and the Pathogenesis of Early-Onset Familial Alzheimer’s Disease: β-Amyloid Production and Parallels to Prion Diseases
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    Chapter 18 Polyene Antibiotics in Experimental Transmissible Subacute Spongiform Encephalopathies
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    Chapter 19 Scrapie Pathogenesis in Brain Grafts
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    Chapter 20 Structural Properties of Recombinant Human Prion Protein
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    Chapter 21 Autonomous Folding and Three-Dimensional Structure of the Carboxy-Terminal Domain of the Mouse Prion Protein, PrP(121–231)
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    Chapter 22 Protease-Resistant Prion Protein Formation
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    Chapter 23 Biophysical Studies on Structure Structural Transitions and Infectivity of the Prion Protein
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    Chapter 24 Amyloidogenesis in Transmissible Spongiform Encephalopathies
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    Chapter 25 Neuronal Degeneration and Cell Death in Prion Disease
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    Chapter 26 Clinical, Pathological, and Molecular Characterization of Gerstmann-Sträussler-Scheinker Disease in the Indiana Kindred ( PRNP F198S)
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    Chapter 27 Studies on the Pathogenesis of Scrapie and the Purification of Scrapie Agent in the Hamster Model
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    Chapter 28 PrP Peptides as a Tool to Investigate the Pathogenesis of Prion Protein Amyloidoses
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    Chapter 29 Properties of the Prion Proteins in Creutzfeldt Jakob Disease Patients Heterozygous for the E200K Mutation
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    Chapter 30 Strain Variation in Scrapie and BSE
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    Chapter 31 Transmission Studies of Fatal Familial Insomnia
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    Chapter 32 Molecular, Genetic and Transgenetic Studies of Human Prion Disease
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    Chapter 33 Molecular Biology of Prion Propagation
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    Chapter 34 Ultrastructural and Immunocytochemical Studies on Prion Pathogenesis
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    Chapter 35 Overview of the BSE Epidemic
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    Chapter 36 Assessing Risks of BSE Transmission to Humans
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    Chapter 37 Human Activities Are Causing Selection of Pathogenic Agents
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    Chapter 38 Pathogenic Similarity of Slow Infections, Induced by Prions and Virions
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    Chapter 39 Protein Folding and Misfolding
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    Chapter 40 CJD Risk Factors: Analysis of 104 Patients
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    Chapter 41 Concluding Talk: Prions from a Physicist’s Viewpoint — Is the ‘Protein Only’ Hypothesis Correct?
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Title
Prions and Brain Diseases in Animals and Humans
Published by
Springer US, June 2013
DOI 10.1007/978-1-4899-1896-3
ISBNs
978-1-4899-1898-7, 978-1-4899-1896-3
Editors

Morrison, Douglas R. O.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 2 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 1 50%
Unknown 1 50%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 1 50%
Unknown 1 50%
Readers by discipline Count As %
Agricultural and Biological Sciences 1 50%
Unknown 1 50%