| Title |
Crucial Functionalizations of Carbon Nanotubes for Improved Drug Delivery: A Valuable Option?
|
|---|---|
| Published in |
Pharmaceutical Research, January 2009
|
| DOI | 10.1007/s11095-008-9811-0 |
| Pubmed ID | |
| Authors |
Giorgia Pastorin |
| Abstract |
Amidst the myriad of drug delivery systems able to enhance delivery, absorption and intracellular uptake of a bioactive molecule while protecting it from deactivation, Carbon Nanotubes (CNTs) have emerged as a recent and promising option especially in cancer therapy. This is mainly due to their unique properties, which render them extremely versatile through the incorporation of several functional groups and targeting molecules at the same time, while their natural shape allows them to selectively penetrate across biological barriers in a non-invasive way. In this expert review we aim to evaluate whether this innovative material, once chemically-modified with suitable functionalizations, can be considered as a valuable system in comparison to the already existing nanodevices. This will include the estimation of the most recent advances in the field of nanotechnology, together with a cautious evaluation of potential risks and hazards associated with the extensive use of this fascinating, but still unknown, nanomaterial. |
Mendeley readers
The data shown below were compiled from readership statistics for 106 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Taiwan | 2 | 2% |
| Mexico | 1 | <1% |
| France | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 101 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 32 | 30% |
| Researcher | 20 | 19% |
| Student > Master | 13 | 12% |
| Student > Bachelor | 11 | 10% |
| Professor | 5 | 5% |
| Other | 12 | 11% |
| Unknown | 13 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 34 | 32% |
| Agricultural and Biological Sciences | 12 | 11% |
| Engineering | 9 | 8% |
| Medicine and Dentistry | 8 | 8% |
| Materials Science | 7 | 7% |
| Other | 20 | 19% |
| Unknown | 16 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 January 2017.
All research outputs
#4,696,673
of 22,789,566 outputs
Outputs from Pharmaceutical Research
#492
of 2,856 outputs
Outputs of similar age
#26,572
of 170,177 outputs
Outputs of similar age from Pharmaceutical Research
#4
of 28 outputs
Altmetric has tracked 22,789,566 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,856 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.0. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 170,177 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 78% of its contemporaries.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.