| Title |
Susceptibility to Lipase-Mediated Digestion Reduces the Oral Bioavailability of Danazol After Administration as a Medium-Chain Lipid-Based Microemulsion Formulation
|
|---|---|
| Published in |
Pharmaceutical Research, August 2004
|
| DOI | 10.1023/b:pham.0000036914.22132.cc |
| Pubmed ID | |
| Authors |
Christopher J. H. Porter, Ann Marie Kaukonen, Ben J. Boyd, Glenn A. Edwards, William N. Charman |
| Abstract |
To investigate the impact of lipidic formulation type on in vitro dispersion and digestion properties and the relationship to oral bioavailability, using danazol as a model lipophilic poorly water-soluble drug. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 93 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 1 | 1% |
| United States | 1 | 1% |
| Ireland | 1 | 1% |
| Unknown | 90 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 18 | 19% |
| Student > Master | 18 | 19% |
| Researcher | 14 | 15% |
| Student > Doctoral Student | 5 | 5% |
| Professor > Associate Professor | 4 | 4% |
| Other | 16 | 17% |
| Unknown | 18 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Pharmacology, Toxicology and Pharmaceutical Science | 27 | 29% |
| Medicine and Dentistry | 16 | 17% |
| Agricultural and Biological Sciences | 13 | 14% |
| Chemistry | 6 | 6% |
| Biochemistry, Genetics and Molecular Biology | 2 | 2% |
| Other | 9 | 10% |
| Unknown | 20 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 August 2022.
All research outputs
#5,240,151
of 25,373,627 outputs
Outputs from Pharmaceutical Research
#519
of 2,982 outputs
Outputs of similar age
#10,578
of 61,344 outputs
Outputs of similar age from Pharmaceutical Research
#10
of 36 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,982 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 61,344 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 36 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.