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Toxicology in Transition

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Cover of 'Toxicology in Transition'

Table of Contents

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    Book Overview
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    Chapter 1 Concepts, Potentials and Methods for Constructing Transgenic Cells and Animals
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    Chapter 2 Use of Recombinant Cells in Metabolic and Mechanistic Studies
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    Chapter 3 Applications for Transgenic Animals in Toxicology
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    Chapter 4 Principles, Benefits and Limitations of the NOEL Approach
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    Chapter 5 Comparison of BMD with NOAEL and LOAEL Values Derived from Subchronic Toxicity Studies
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    Chapter 6 Biomarkers in Ecotoxicology: an Overview
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    Chapter 7 Use of cytochrome P450 1A (CYP1A) in fish as a biomarker of aquatic pollution
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    Chapter 8 Cellular and molecular biology of aryl hydrocarbon (Ah) receptor-mediated gene expression.
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    Chapter 9 Inhibitors of the Sodium Pump: Toxins, then Drugs, and now hormones
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    Chapter 10 Rodent Responses To Peroxisome Proliferators — A Receptor-Mediated Phenomenon?
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    Chapter 11 Role of Second Messengers in Mineral Particle-Induced Production of Reactive Oxygen Species by Phagocytes
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    Chapter 12 Estrogenic Effects of Some Xenobiotics
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    Chapter 13 In Vitro Methods in Regulatory Toxicology: The Crucial Significance of Validation
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    Chapter 14 Scientific, ethical and legal aspects of the acceptance of in vitro methods in regulatory toxicology
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    Chapter 15 The Validation and Use of In Vitro Teratogenicity Tests
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    Chapter 16 In Vitro Methods in Regulatory Toxicology
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    Chapter 17 In Vitro Tests in Regulatory Toxicology: Symposium Chairman’s Summing-up
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    Chapter 18 Ex Vivo and in Vitro Models in Acetaminophen Hepatotoxicity Studies. Relationship between Glutathione Depletion, Oxidative Stress and Disturbances in Calcium Homeostasis and Energy Metabolism
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    Chapter 19 Rabbit Renal Proximal Tubule Suspensions as a Model for Nephrotoxicity Evaluation of Native or in situ Metabolized β-Lactam Antibiotics
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    Chapter 20 Neurobehavioral Abnormalities Induced by Prenatal Exposure to Substances of Abuse — Stating the Problems
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    Chapter 21 Prenatal exposure to marihuana and tobacco during infancy, early and middle childhood: effects and an attempt at synthesis.
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    Chapter 22 Delayed Developmental Neuro- and Immunotoxicity of Benzodiazepines
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    Chapter 23 Changes in EEG of freely-moving rats caused by three-generation organophosphate treatment
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    Chapter 24 Developmental Neurotoxicity of Carbon Monoxide
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    Chapter 25 The Safety Assessment of Over-The-Counter (OTC) Products
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    Chapter 26 OTC Pharmaceuticals and Genotoxicity Testing: The Paracetamol, Anthraquinone, and Griseofulvin Cases
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    Chapter 27 Safety Assessment of OTC Drugs: Doxylamine Succinate
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    Chapter 28 Safety Assessment of OTC Products — A Regulatory View
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    Chapter 29 Drug toxicity findings and no action taken
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    Chapter 30 Species Specificity of Organ Toxicity
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    Chapter 31 Species Specificity at the Molecular Level: the Case of Nitric Oxide Synthases
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    Chapter 32 Mechanisms Underlying Species-Specificity in Target Organ Toxicity
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    Chapter 33 Species Specificity of Organ Toxicity: Behavioral Differences
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    Chapter 34 Development of OECD Test Guidelines and Hazard Assessment Procedures for Terrestrial Effects
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    Chapter 35 Development of Guidance for Terrestrial Effects Assessment
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    Chapter 36 Application of Quick and Simple Plant Bioassays to Assess the Genotoxicity of Environmental Pollutants — Detection of Potential Health Hazards of Air, Water and Soil contaminants
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    Chapter 37 Comparison of susceptibilities of species used in toxicological and environmental risk assessment to chemicals (pesticides)
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    Chapter 38 Toxicological Evaluation of Pollutants in Soil — Concept of the AGU and Assessment of Tolerable Concentrations for Metals
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    Chapter 39 The SCID (Severe Combined Immunodeficiency) Mouse — Its Biology and Use in Immunotoxicological Research
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    Chapter 40 The SCID Mouse as a Tool to Bridge the Gap Between Animal and Human Responses
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    Chapter 41 The SCID Mouse and its use for Immunopharmacological and Immunotoxicological Investigations
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    Chapter 42 Chirality — from Molecules to Organisms
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    Chapter 43 Interactions between the in vitro metabolism of xenobiotics and fatty acids
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    Chapter 44 Side effects and toxic reactions of chiral drugs: A clinical perspective
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    Chapter 45 Analysis of (S)- and (R)-Propranolol in Human Plasma and Urine by a Specific Immunoenzymatic Assay versus HPLC
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    Chapter 46 Biological Behavior of Prestages of Cancer Cells: An Introduction
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    Chapter 47 Preneoplastic Lesions In Kidney And Carcinogenesis By Non-Genotoxic Compounds
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    Chapter 48 Early Cellular Alterations in Chemical Liver Carcinogenesis as Assessed by Immunohistochemical and Molecular Biological Techniques
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    Chapter 49 The UK Approach to the Regulation and Evaluation of Novel Foods Produced by Biotechnology
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    Chapter 50 Molecular Mimicry of CF 3 CO-Lysine by Lipoic Acid I: The Dihydrolipoamide Acetyltransferase Subunit of the Human Pyruvate Dehydrogenase as Autoantigen in Halothane Hepatitis
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    Chapter 51 Molecular Mimicry of CF 3 CO-Lys by Lipoic Acid II: Lipoic Acid Bearing Proteins as Autoantigens in Halothane Hepatitis
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Title
Toxicology in Transition
Published by
Springer Berlin Heidelberg, December 2012
DOI 10.1007/978-3-642-79451-3
ISBNs
978-3-64-279453-7, 978-3-64-279451-3
Editors

Degen, Gisela H., Seiler, Jürg P., Bentley, Philip

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 5 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 20%
Unknown 4 80%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 60%
Professor 1 20%
Student > Bachelor 1 20%
Professor > Associate Professor 1 20%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 2 40%
Arts and Humanities 1 20%
Agricultural and Biological Sciences 1 20%
Psychology 1 20%
Medicine and Dentistry 1 20%
Other 0 0%