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Are recently identified genetic variants regulating BMI in the general population associated with anorexia nervosa?

Overview of attention for article published in American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics: The Official Publication of the International Society of Psychiatric Genetics, February 2010
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Title
Are recently identified genetic variants regulating BMI in the general population associated with anorexia nervosa?
Published in
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics: The Official Publication of the International Society of Psychiatric Genetics, February 2010
DOI 10.1002/ajmg.b.31026
Pubmed ID
Authors

Marek K. Brandys, Annemarie A. van Elburg, Ruth J.F. Loos, Florianne Bauer, Judith Hendriks, Yvonne T. van der Schouw, Roger A.H. Adan

Abstract

The influence of body mass index (BMI) on susceptibility to anorexia nervosa (AN) is not clear. Recently published genome-wide association (GWA) studies of the general population identified several variants influencing BMI. We genotyped these variants in an AN sample to test for association and to investigate a combined effect of BMI-increasing alleles (as determined in the original GWA studies) on the risk of developing the disease. Individual single nucleotide polymorphisms (SNPs) were tested for association with AN in a sample of 267 AN patients and 1,636 population controls. A logistic regression for the combined effect of BMI-increasing alleles included 225 cases and 1,351 controls. We found no significant association between individual SNPs and AN. The analysis of a combined effect of BMI-increasing alleles showed absence of association with the investigated condition. The percentages of BMI-increasing alleles were equal between cases and controls. This study found no evidence that genetic variants regulating BMI in the general population are significantly associated with susceptibility to AN.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 8%
Unknown 22 92%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 5 21%
Student > Master 4 17%
Student > Ph. D. Student 3 13%
Student > Postgraduate 2 8%
Professor 2 8%
Other 3 13%
Unknown 5 21%
Readers by discipline Count As %
Psychology 6 25%
Medicine and Dentistry 4 17%
Neuroscience 2 8%
Social Sciences 2 8%
Business, Management and Accounting 1 4%
Other 4 17%
Unknown 5 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 July 2018.
All research outputs
#8,550,571
of 25,411,814 outputs
Outputs from American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics: The Official Publication of the International Society of Psychiatric Genetics
#437
of 1,158 outputs
Outputs of similar age
#38,651
of 103,136 outputs
Outputs of similar age from American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics: The Official Publication of the International Society of Psychiatric Genetics
#9
of 15 outputs
Altmetric has tracked 25,411,814 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,158 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one is in the 42nd percentile – i.e., 42% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 103,136 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one is in the 6th percentile – i.e., 6% of its contemporaries scored the same or lower than it.