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Handbook of Anticancer Pharmacokinetics and Pharmacodynamics

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Cover of 'Handbook of Anticancer Pharmacokinetics and Pharmacodynamics'

Table of Contents

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    Book Overview
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    Chapter 1 Molecular Targets
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    Chapter 2 Preclinical Screening for New Anticancer Agents
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    Chapter 3 Natural Product Screening
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    Chapter 4 Defining the Starting Dose: Should It Be mg/kg, mg/m 2 , or Fixed?
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    Chapter 5 Phase 0 Trials in Oncology
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    Chapter 6 Phase I Trials in Oncology: Design and Endpoints
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    Chapter 7 Quantitative Analytical Methods: Development and Clinical Considerations
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    Chapter 8 Validation and Control of Bioanalytical Methods
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    Chapter 9 Anticancer Clinical Pharmacology Overview
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    Chapter 10 Pharmacokinetic Modeling
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    Chapter 11 Pharmacometrics
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    Chapter 12 Pharmacodynamic Modeling
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    Chapter 13 Protein Binding
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    Chapter 14 Metabolism (Non-CYP Enzymes)
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    Chapter 15 Pharmacogenomics and Cancer Therapy: Somatic and Germline Polymorphisms
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    Chapter 16 Cytochrome P450
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    Chapter 17 Polymorphisms in Genes of Drug Targets and Metabolism
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    Chapter 18 DNA Repair: ERCC1, Nucleotide Excision Repair, and Platinum Resistance
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    Chapter 19 Drug Interactions
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    Chapter 20 ABC Transporters: Involvement in Multidrug Resistance and Drug Disposition
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    Chapter 21 Solute Carriers
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    Chapter 22 High-Throughput Platforms in Drug Metabolism and Transport Pharmacogenetics
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    Chapter 23 Intrathecal Administration
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    Chapter 24 Microdialysis
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    Chapter 25 Regional Drug Delivery for Inoperable Pulmonary Malignancies
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    Chapter 26 Blood–Brain Barrier and CNS Malignancy
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    Chapter 27 Radiation and Altering Clinical Pharmacology
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    Chapter 28 Therapeutic Cancer Vaccines: An Emerging Approach to Cancer Treatment
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    Chapter 29 Recombinant Immunotoxins
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    Chapter 30 Monoclonal Antibodies
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    Chapter 31 Clinical Pharmacology in Pediatrics
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    Chapter 32 Clinical Pharmacology in the Older Adult
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    Chapter 33 Organ Dysfunction Trials: Background, Historical Barriers, Progress in Overcoming Barriers, and Suggestions for Future Trials
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    Chapter 34 Drug Formulations: How these Affects Anticancer Drug
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    Chapter 35 Nanotechnology in Cancer
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    Chapter 36 Imaging in Drug Development
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    Chapter 37 Exposure–Response Relationships of Anticancer Agents: Application in Drug Development and Drug Label
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    Chapter 38 The Role of Phase III Trials in Modern Drug Development
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    Chapter 39 Clinical Trial Designs for Approval of New Anticancer Agents
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    Chapter 40 Clinical Pharmacogenetics
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Title
Handbook of Anticancer Pharmacokinetics and Pharmacodynamics
Published by
Springer New York, January 2014
DOI 10.1007/978-1-4614-9135-4
ISBNs
978-1-4614-9134-7, 978-1-4614-9135-4
Editors

Rudek, Michelle A., Chau, Cindy H., Figg, William D., McLeod, Howard L.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 447 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 447 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 2 <1%
Professor > Associate Professor 1 <1%
Student > Ph. D. Student 1 <1%
Unknown 443 99%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 2 <1%
Biochemistry, Genetics and Molecular Biology 1 <1%
Unknown 444 99%