| Title |
Soluble phosphate glass fibres for repair of bone-ligament interface
|
|---|---|
| Published in |
Journal of Materials Science: Materials in Medicine, December 2005
|
| DOI | 10.1007/s10856-005-4718-3 |
| Pubmed ID | |
| Authors |
M. Bitar, J. C. Knowles, M. P. Lewis, V. Salih |
| Abstract |
Phosphate-based fibres of the generic composition (CaO)0.46-(Na2O)n-(Fe2O3)y-(P2O5)0.50 have been evaluated, in vitro, as three dimensional scaffolds for tissue engineering of the hard-soft tissue interface by assessing the fibre solubility and growth and functional gene expression of human cells. Primary human osteoblasts and fibroblasts were seeded onto scaffolds and maintained in culture for up to 21 days. Fluorescent immunolabeling revealed the spread cell morphology and significant proliferation pattern on these fibres, particularly on the 3 mol% Fe2O3-containing formulation. Real-time quantitative Polymerase Chain Reaction (rtQ-PCR) analysis of gene expression using TaqMan Probes was preformed and it has been established that committed cell differentiation was maintained by both cell types, and was strongly related to the 3 mol% Fe2O3 glass composition. These novel, readily manufactured, soluble glass fibres offer a biocompatible and biochemically favourable alternative in the search for suitable degradable materials used in Tissue Engineering. |
Mendeley readers
The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 4% |
| Latvia | 1 | 2% |
| United States | 1 | 2% |
| Unknown | 50 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 16 | 30% |
| Researcher | 9 | 17% |
| Student > Master | 5 | 9% |
| Student > Bachelor | 3 | 6% |
| Professor > Associate Professor | 3 | 6% |
| Other | 9 | 17% |
| Unknown | 9 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Materials Science | 13 | 24% |
| Engineering | 8 | 15% |
| Chemistry | 6 | 11% |
| Agricultural and Biological Sciences | 5 | 9% |
| Medicine and Dentistry | 5 | 9% |
| Other | 5 | 9% |
| Unknown | 12 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 November 2023.
All research outputs
#4,696,673
of 22,789,566 outputs
Outputs from Journal of Materials Science: Materials in Medicine
#106
of 1,402 outputs
Outputs of similar age
#18,506
of 146,534 outputs
Outputs of similar age from Journal of Materials Science: Materials in Medicine
#1
of 16 outputs
Altmetric has tracked 22,789,566 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,402 research outputs from this source. They receive a mean Attention Score of 3.4. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 146,534 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.