Title |
Vitamin D in schizophrenia, major depression and alcoholism
|
---|---|
Published in |
Journal of Neural Transmission, July 2000
|
DOI | 10.1007/s007020070063 |
Pubmed ID | |
Authors |
B. Schneider, B. Weber, A. Frensch, J. Stein, J. Fritze |
Abstract |
25-Hydroxyvitamin D3, 1,25-dihydroxyvitamin D3, calcium, phosphate and parathyreoidal hormone levels were assessed in 34 patients with schizophrenia (DSM-III-R, 44% female, mean age 38.9 +/- 2.1 years), 30 patients with alcohol addiction (16% female, mean age 48.7 +/- 2.2 years), 25 patients with major depression (56% female, mean age 57.6+/- years) and 31 healthy controls. Only 25-hydroxyvitamin D3 and 1,25-dihydroxvitamin D3 levels were significantly lower in all groups of psychiatric patients than in normal controls, but not phosphate, calcium and parathyreoidal hormone levels. Significant differences in the vitamin D levels could not be found between the three psychiatric groups. These findings do not support the idea that vitamin D is specifically involved in the pathophysiology of depression. The difference in patients as compared to the healthy controls might be related to a different social background resulting in differing habits e.g. of nutrition. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 3 | 3% |
United States | 1 | 1% |
Poland | 1 | 1% |
Unknown | 82 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 15 | 17% |
Other | 11 | 13% |
Student > Ph. D. Student | 11 | 13% |
Student > Bachelor | 11 | 13% |
Researcher | 9 | 10% |
Other | 19 | 22% |
Unknown | 11 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 29 | 33% |
Agricultural and Biological Sciences | 9 | 10% |
Neuroscience | 8 | 9% |
Nursing and Health Professions | 7 | 8% |
Psychology | 7 | 8% |
Other | 16 | 18% |
Unknown | 11 | 13% |