| Title |
Pulmonary manifestation of a Langerhans cell sarcoma: case report and review of the literature
|
|---|---|
| Published in |
Virchows Archiv, November 2005
|
| DOI | 10.1007/s00428-005-0115-z |
| Pubmed ID | |
| Authors |
Boris Dominik Jülg, Sven Weidner, Doris Mayr |
| Abstract |
In the following, we describe the very rare case of Langerhans cell sarcoma (LCS) in the lung. Throughout the medical literature, only a few cases have been published, and, to the best of our knowledge, this is the first case to be reported in Germany. The patient was an 81-year-old man who showed symptoms such as chronic cough and weight loss. Clinical examination including needle biopsy indicated a high possibility of carcinoma in the right lung and in the mediastinum; however, the final histopathological diagnosis after immunohistochemistry gave evidence of LCS. LCS is a neoplastic proliferation of Langerhans cells with malignant cytological features exhibiting a very aggressive behaviour. LCS can be distinguished from other carcinomas, lymphomas and sarcomas by the typical morphological features of Langerhans cells and the immunophenotype with a consistent expression of S-100 protein and CD1a. In contrast to Langerhans cell histiocytosis, the LCS consists of Langerhans cells with high atypia and a very high mitotic rate. |
Mendeley readers
The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 16 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Professor > Associate Professor | 4 | 25% |
| Student > Bachelor | 4 | 25% |
| Other | 3 | 19% |
| Researcher | 2 | 13% |
| Student > Postgraduate | 1 | 6% |
| Other | 0 | 0% |
| Unknown | 2 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 8 | 50% |
| Engineering | 2 | 13% |
| Agricultural and Biological Sciences | 2 | 13% |
| Biochemistry, Genetics and Molecular Biology | 1 | 6% |
| Unknown | 3 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 March 2009.
All research outputs
#7,454,427
of 22,789,566 outputs
Outputs from Virchows Archiv
#410
of 1,951 outputs
Outputs of similar age
#37,805
of 146,093 outputs
Outputs of similar age from Virchows Archiv
#4
of 7 outputs
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