| Title |
Role of Acid-Sensing Ion Channel 3 in Sub-Acute-Phase Inflammation
|
|---|---|
| Published in |
Molecular Pain, January 2009
|
| DOI | 10.1186/1744-8069-5-1 |
| Pubmed ID | |
| Authors |
Yi-Tin Yen, Pan-Hsien Tu, Chien-Ju Chen, Yi-Wen Lin, Sung-Tsang Hsieh, Chih-Cheng Chen |
| Abstract |
Inflammation-mediated hyperalgesia involves tissue acidosis and sensitization of nociceptors. Many studies have reported increased expression of acid-sensing ion channel 3 (ASIC3) in inflammation and enhanced ASIC3 channel activity with pro-inflammatory mediators. However, the role of ASIC3 in inflammation remains inconclusive because of conflicting results generated from studies of ASIC3 knockout (ASIC3-/-) or dominant-negative mutant mice, which have shown normal, decreased or increased hyperalgesia during inflammation. |
Mendeley readers
The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Hong Kong | 1 | 2% |
| Canada | 1 | 2% |
| Unknown | 44 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 12 | 26% |
| Researcher | 8 | 17% |
| Student > Doctoral Student | 3 | 7% |
| Lecturer | 2 | 4% |
| Professor > Associate Professor | 2 | 4% |
| Other | 7 | 15% |
| Unknown | 12 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 10 | 22% |
| Medicine and Dentistry | 5 | 11% |
| Neuroscience | 5 | 11% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 7% |
| Biochemistry, Genetics and Molecular Biology | 3 | 7% |
| Other | 7 | 15% |
| Unknown | 13 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 August 2013.
All research outputs
#5,446,210
of 25,371,288 outputs
Outputs from Molecular Pain
#106
of 669 outputs
Outputs of similar age
#28,938
of 183,276 outputs
Outputs of similar age from Molecular Pain
#7
of 24 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 669 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 183,276 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 78% of its contemporaries.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.