| Title |
Collapsin Response Mediator Proteins Regulate Neuronal Development and Plasticity by Switching Their Phosphorylation Status
|
|---|---|
| Published in |
Molecular Neurobiology, February 2012
|
| DOI | 10.1007/s12035-012-8242-4 |
| Pubmed ID | |
| Authors |
Naoya Yamashita, Yoshio Goshima |
| Abstract |
Collapsin response mediator protein (CRMP) was originally identified as a molecule involved in semaphorin3A signaling. CRMPs are now known to consist of five homologous cytosolic proteins, CRMP1-5. All of them are phosphorylated and highly expressed in the developing and adult nervous system. In vitro experiments have clearly demonstrated that CRMPs play important roles in neuronal development and maturation through the regulation of their phosphorylation. Several recent knockout mice studies have revealed in vivo roles of CRMPs in neuronal migration, neuronal network formation, synapse formation, synaptic plasticity, and neuronal diseases. Dynamic spatiotemporal regulation of phosphorylation status of CRMPs is involved in many aspects of neuronal development. |
Mendeley readers
The data shown below were compiled from readership statistics for 82 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Sweden | 1 | 1% |
| South Africa | 1 | 1% |
| Unknown | 80 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 17 | 21% |
| Student > Ph. D. Student | 17 | 21% |
| Student > Bachelor | 15 | 18% |
| Researcher | 8 | 10% |
| Student > Doctoral Student | 6 | 7% |
| Other | 8 | 10% |
| Unknown | 11 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 29 | 35% |
| Neuroscience | 19 | 23% |
| Biochemistry, Genetics and Molecular Biology | 12 | 15% |
| Medicine and Dentistry | 6 | 7% |
| Nursing and Health Professions | 2 | 2% |
| Other | 2 | 2% |
| Unknown | 12 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 December 2023.
All research outputs
#7,454,427
of 22,789,566 outputs
Outputs from Molecular Neurobiology
#1,349
of 3,443 outputs
Outputs of similar age
#51,495
of 155,988 outputs
Outputs of similar age from Molecular Neurobiology
#5
of 13 outputs
Altmetric has tracked 22,789,566 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,443 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one has gotten more attention than average, scoring higher than 54% of its peers.
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We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.