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Protein Conformation as an Immunological Signal

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Cover of 'Protein Conformation as an Immunological Signal'

Table of Contents

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    Book Overview
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    Chapter 1 Introduction
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    Chapter 2 Antibody-Hapten Binding Kinetics, Conformational Transitions and Domains Interactions
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    Chapter 3 Dynamic Aspects of Signal Transfer in Antibody Molecules
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    Chapter 4 Could Aggregation of Human Immunoglobulins Bring about Appearance of Novel Antigenic Sites?
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    Chapter 5 Introduction
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    Chapter 6 Immunoglobulin M Conformational Change is a Signal for Complement Activation
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    Chapter 7 Expression of Fc Effector Function in Homogeneous Murine Anti-Ars IgM
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    Chapter 8 The Localization of Effector Sites on Immunoglobulin G
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    Chapter 9 Human Fcγ Fragment: Location of Acidic Residues Involved in Complement Activation
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    Chapter 10 Introduction
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    Chapter 11 Ultrastructure of the First Component Of Human Complement
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    Chapter 12 Binding of Human I 125 Fibronectin to C1q and to Human Monoclonal Myeloma IgG Subclasses
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    Chapter 13 Biochemical Specificity of Human Complement Component C1q
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    Chapter 14 Sequence Studies on Human Complement Subcomponent $$ {\rm{C\bar 1r}} $$
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    Chapter 15 Introduction
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    Chapter 16 Dissociation of C1 and Concentration Dependence of Its Activation Kinetics
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    Chapter 17 Fluid Phase Activation of Proenzymic C1r
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    Chapter 18 Activation of Mammalian Complement by Chicken C1q
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    Chapter 19 Introduction
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    Chapter 20 Conformational Antigenic Determinants in Proteins
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    Chapter 21 Topographic Antigenic Determinants Detected by Monoclonal Antibodies to Myoglobin
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    Chapter 22 Role of Conformation on the Antigenic Determinants of Tobacco Mosaic Virus Protein
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    Chapter 23 Monoclonal Antibodies may Block Sterically or Conformationally the Antigenic Determinants of Human Growth Hormone
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    Chapter 24 An Immunochemical Study of the Changes in Conformation Undergone by Two Domains of the Tryptophan-Synthetase β 2 Subunit upon Association
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    Chapter 25 Introduction
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    Chapter 26 Antibody-Mediated Activation of Genetically Defective Escherichia Coli Galactosidases by Monoclonal Antibodies
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    Chapter 27 Synergistic Activation by Monoclonal Antibodies of β-Galactosidase from Genetically Defective E. Coli
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    Chapter 28 Antibodies as Probes of Protein Structure
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    Chapter 29 Is There a Preferential Pathway for Antibody-Mediated Enzyme Activation?
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    Chapter 30 General Introduction
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    Chapter 31 T Lymphocyte Recognition of Small Peptide Antigens: Formation of Neoantigenic Determinants and Clonal Frequency Resulting in IR Gene Control
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    Chapter 32 The Antigenic Structure of Bovine Serum Albumin: T-Cell, B-Cell, And Ia Determinants
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    Chapter 33 Attempts to Understand the Function of Macrophages and Antigen Specific Cells in their Mutual Interaction
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    Chapter 34 A Possible Immunodominant Domain on Myoglobin Recognized by T Lymphocytes
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    Chapter 35 Antigen Presenting Function of Macrophages
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    Chapter 36 The Sorting-Out Problem in Antigen Presentation
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    Chapter 37 Genetic Analysis of Responsiveness to Adjuvant-Free Immunological Signals: Transfer of Genes from Responder Strains (SJL/J And CE/J) to a Nonresponder Background Uncovers a Requirement for H-2 Heterozygosity
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    Chapter 38 How is Adjuvanticity Recognised?
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    Chapter 39 Specificity and Restriction of T Cells in a System of Complementing Ir Genes
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    Chapter 40 Evidence for Ia — Antigen Interaction in T Cell Activation
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    Chapter 41 Somatic T Cell Hybrids in the Analysis of H-2 Restriction and Antigen Recognition
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    Chapter 42 Introduction
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    Chapter 43 Antigen Bridging in T Cell-B Cell Interaction: Fact or Fiction?
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    Chapter 44 B Cells as MHC Restricted Antigen Presenting Cells: A Model for T-B Interaction
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    Chapter 45 A View from the Bridge: Antigenic Determinants in Immunoregulation
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    Chapter 46 Antigen Structures used by Regulatory T Cells in the Interaction among T Suppressor, T Helper and B Cells
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    Chapter 47 Activation of Human B Lymphocytes by Antigen Specific T Cell Lines
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    Chapter 48 T Helper Cell Recognition of Two Types of Mouse Lambda Light Chains
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    Chapter 49 Effects of Anti-Idiotypic Sera (Ab-2) and Monoclonal Idiotypic Antibody (Ab-1) on the Immune Response to a Simple Polypeptide Antigen with only Two Immunologically Active Epitopes. Analysis of the Response at the Unideterminant Level
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    Chapter 50 Introduction
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    Chapter 51 The Role of IgE and Its Receptor in Mediating Secretion
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    Chapter 52 A New Method for Monitoring Intracellular Free Ca 2+ in Lymphocytes. Concanavalin A and Anti-Ig m Induce an Early Rise of Cytoplasmic Free Ca 2+
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    Chapter 53 B Lymphocyte Stimulation and Suppression by the Fc Portion of Immunoglobulin
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    Chapter 54 Modulation of Immunological Reactivity by the Fc Piece of Immunoglobulin
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    Chapter 55 T Cell Replacing Factor (TRF)-Induced IgG Production in a Human B Cell Line and the Mechanism of Transmembrane Signaling through TRF-Acceptors
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Title
Protein Conformation as an Immunological Signal
Published by
Springer US, December 2012
DOI 10.1007/978-1-4613-3778-2
ISBNs
978-1-4613-3780-5, 978-1-4613-3778-2
Editors

Celada, Franco, Schumaker, Verne N., Sercarz, Eli E.