| Title |
A Twin Study of ADHD Symptoms in Early Adolescence: Hyperactivity-impulsivity and Inattentiveness Show Substantial Genetic Overlap but Also Genetic Specificity
|
|---|---|
| Published in |
Research on Child and Adolescent Psychopathology, August 2010
|
| DOI | 10.1007/s10802-010-9451-9 |
| Pubmed ID | |
| Authors |
Corina U. Greven, Frühling V. Rijsdijk, Robert Plomin |
| Abstract |
A previous paper in this journal revealed substantial genetic overlap between the ADHD dimensions of hyperactivity-impulsivity and inattentiveness in a sample of 8-year old twins drawn from a UK-representative population sample. Four years later, when the twins were 12 years old, more than 5,500 pairs drawn from the same sample were rated again on the DSM-IV based Revised Conners' Parent Rating Scale to assess symptoms on both ADHD dimensions. Heritabilities were high (around 70%) for both hyperactivity-impulsivity and inattentiveness and evidence for etiological sex differences was absent. The critical finding was a genetic correlation of 0.55, indicating that hyperactivity-impulsivity and inattentiveness are substantially influenced by the same genes but that the two dimensions also show large and significant unique genetic effects. These results in early adolescence confirm our findings in middle childhood, providing evidence for substantial genetic overlap as well as genetic heterogeneity of the ADHD dimensions. Future genetic studies should investigate the ADHD dimensions separately. |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 132 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 2% |
| Netherlands | 2 | 2% |
| Canada | 1 | <1% |
| Unknown | 127 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 32 | 24% |
| Student > Ph. D. Student | 25 | 19% |
| Student > Bachelor | 25 | 19% |
| Researcher | 10 | 8% |
| Student > Doctoral Student | 8 | 6% |
| Other | 21 | 16% |
| Unknown | 11 | 8% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 58 | 44% |
| Agricultural and Biological Sciences | 16 | 12% |
| Medicine and Dentistry | 14 | 11% |
| Neuroscience | 13 | 10% |
| Nursing and Health Professions | 4 | 3% |
| Other | 14 | 11% |
| Unknown | 13 | 10% |
Attention Score in Context
This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 November 2020.
All research outputs
#2,485,550
of 25,373,627 outputs
Outputs from Research on Child and Adolescent Psychopathology
#223
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Outputs of similar age
#9,223
of 104,132 outputs
Outputs of similar age from Research on Child and Adolescent Psychopathology
#3
of 24 outputs
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