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Hedonistic homeostatic dysregulation in patients with Parkinson's disease on dopamine replacement therapies

Overview of attention for article published in Journal of neurology, neurosurgery and psychiatry, April 2000
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (94th percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

Mentioned by

blogs
1 blog
twitter
6 X users
wikipedia
2 Wikipedia pages

Citations

dimensions_citation
530 Dimensions

Readers on

mendeley
221 Mendeley
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Title
Hedonistic homeostatic dysregulation in patients with Parkinson's disease on dopamine replacement therapies
Published in
Journal of neurology, neurosurgery and psychiatry, April 2000
DOI 10.1136/jnnp.68.4.423
Pubmed ID
Authors

G Giovannoni, J D O'Sullivan, K Turner, A J Manson, A J Lees

Abstract

Hedonistic homeostatic dysregulation is a neuropsychological behavioural disorder associated with substance misuse and addiction. The disorder has been recognised as a consequence of dopamine replacement therapy (DRT) in 15 patients with Parkinson's disease. The syndrome typically develops in male patients with early onset Parkinson's disease, and can occur with orally and subcutaneously administered DRT. These patients take increasing quantities of their DRT, despite increasingly severe drug induced dyskinesias, and may develop a cyclical mood disorder with hypomania or manic psychosis. There is impairment of social and occupational functioning. Tolerance develops to mood elevating effects of DRT and a negative affective withdrawal state occurs if the drugs are withdrawn or doses decreased. The clinical features and guidelines for managing this syndrome are discussed. A set of diagnostic criteria for further investigating this condition is proposed.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 221 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 4 2%
Switzerland 2 <1%
United States 2 <1%
United Kingdom 2 <1%
Italy 1 <1%
Germany 1 <1%
Finland 1 <1%
Slovenia 1 <1%
Canada 1 <1%
Other 0 0%
Unknown 206 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 36 16%
Student > Ph. D. Student 34 15%
Student > Master 26 12%
Student > Bachelor 25 11%
Student > Doctoral Student 17 8%
Other 54 24%
Unknown 29 13%
Readers by discipline Count As %
Medicine and Dentistry 70 32%
Psychology 48 22%
Neuroscience 33 15%
Agricultural and Biological Sciences 10 5%
Social Sciences 4 2%
Other 8 4%
Unknown 48 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 December 2023.
All research outputs
#2,570,399
of 25,394,764 outputs
Outputs from Journal of neurology, neurosurgery and psychiatry
#1,423
of 7,408 outputs
Outputs of similar age
#2,117
of 40,979 outputs
Outputs of similar age from Journal of neurology, neurosurgery and psychiatry
#3
of 36 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,408 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.9. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 40,979 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 36 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.