| Title |
Preclinical Safety Assessment of the 5-HT2A Receptor Agonist PET Radioligand [11C]Cimbi-36
|
|---|---|
| Published in |
Molecular Imaging and Biology, January 2013
|
| DOI | 10.1007/s11307-012-0609-4 |
| Pubmed ID | |
| Authors |
Anders Ettrup, Søren Holm, Martin Hansen, Muhammad Wasim, Martin Andreas Santini, Mikael Palner, Jacob Madsen, Claus Svarer, Jesper Langgaard Kristensen, Gitte Moos Knudsen |
| Abstract |
[11C]Cimbi-36 was recently developed as an agonist radioligand for brain imaging of serotonin 2A receptors (5-HT2A) with positron emission tomography (PET). This may be used to quantify the high-affinity state of 5-HT2A receptors and may have the potential to quantify changes in cerebral 5-HT levels in vivo. We here investigated safety aspects related to clinical use of [11C]Cimbi-36, including radiation dosimetry and in vivo pharmacology. |
Mendeley readers
The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 2% |
| Denmark | 1 | 2% |
| Unknown | 42 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 17 | 39% |
| Student > Ph. D. Student | 6 | 14% |
| Student > Master | 5 | 11% |
| Student > Bachelor | 4 | 9% |
| Other | 2 | 5% |
| Other | 2 | 5% |
| Unknown | 8 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 7 | 16% |
| Agricultural and Biological Sciences | 6 | 14% |
| Medicine and Dentistry | 5 | 11% |
| Neuroscience | 5 | 11% |
| Biochemistry, Genetics and Molecular Biology | 2 | 5% |
| Other | 9 | 20% |
| Unknown | 10 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 June 2017.
All research outputs
#8,533,995
of 25,371,288 outputs
Outputs from Molecular Imaging and Biology
#244
of 837 outputs
Outputs of similar age
#88,840
of 290,205 outputs
Outputs of similar age from Molecular Imaging and Biology
#3
of 4 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
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