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Evaluation of polybrominated diphenyl ethers (PBDEs) in matched cat sera and house dust samples: Investigation of a potential link between PBDEs and spontaneous feline hyperthyroidism

Overview of attention for article published in Environmental Research, November 2014
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • Good Attention Score compared to outputs of the same age and source (71st percentile)

Mentioned by

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1 news outlet
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1 X user

Citations

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34 Dimensions

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42 Mendeley
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Title
Evaluation of polybrominated diphenyl ethers (PBDEs) in matched cat sera and house dust samples: Investigation of a potential link between PBDEs and spontaneous feline hyperthyroidism
Published in
Environmental Research, November 2014
DOI 10.1016/j.envres.2014.09.027
Pubmed ID
Authors

K. Chow, L.K. Hearn, M. Zuber, J.A. Beatty, J.F. Mueller, V.R. Barrs

Abstract

The cause of feline hyperthyroidism (FH), a common endocrinopathy of domestic cats, is unknown. A potential association between exposure to environmental contaminants polybrominated diphenyl ethers (PBDEs) and FH was investigated. The median serum level for the sum of congeners BDE-47, BDE-99, BDE-153, BDE-154 and BDE-183 (Σ5) in hyperthyroid and euthyroid cats was 82 and 174 ng g(-1)lw respectively with no significant difference in PBDE levels or profiles between groups. Overall, the median (min to max) concentration of PBDEs in cat serum (n=65) was 118 ng g(-1)lw (5-5260 ng g(-1)lw), which is approximately 10 times higher than that observed in the Australian human population. Furthermore, congener composition in feline serum samples was dominated by congener BDE-99, followed by BDE-47 then BDE-153 which differs from results of human biomonitoring. There was no correlation between PBDE levels in feline serum samples and matched house dust samples (n=25). However the similarity of BDE-47/99 ratio in each matrix suggests dust is likely the dominant exposure. Calculation of the daily exposure dose via dust ingestion for cats equated to a mean of 33 ng kg(-1) bw d(-1) (0.2-150 ng kg(-1) bw d(-1)). Differences in exposure estimates for Australian and US cats, based on dust ingestion alone, are consistent with the observed differences in body burdens. Our results do not support a role for PBDE exposure in the aetiopathogenesis of FH.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Pakistan 1 2%
Unknown 41 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 7 17%
Researcher 6 14%
Student > Ph. D. Student 6 14%
Student > Postgraduate 4 10%
Student > Master 3 7%
Other 5 12%
Unknown 11 26%
Readers by discipline Count As %
Environmental Science 5 12%
Veterinary Science and Veterinary Medicine 4 10%
Chemistry 4 10%
Biochemistry, Genetics and Molecular Biology 2 5%
Agricultural and Biological Sciences 2 5%
Other 8 19%
Unknown 17 40%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 April 2015.
All research outputs
#3,710,762
of 25,377,790 outputs
Outputs from Environmental Research
#1,694
of 7,951 outputs
Outputs of similar age
#50,179
of 369,151 outputs
Outputs of similar age from Environmental Research
#20
of 69 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,951 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.5. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 369,151 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 69 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.