| Title |
Effect of Low-Intensity Microwave Radiation on Monoamine Neurotransmitters and Their Key Regulating Enzymes in Rat Brain
|
|---|---|
| Published in |
Cell Biochemistry and Biophysics, February 2015
|
| DOI | 10.1007/s12013-015-0576-x |
| Pubmed ID | |
| Authors |
Kanu Megha, Pravin S. Deshmukh, Alok K. Ravi, Ashok K. Tripathi, Mahesh P. Abegaonkar, Basu D. Banerjee |
| Abstract |
The increasing use of wireless communication devices has raised major concerns towards deleterious effects of microwave radiation on human health. The aim of the study was to demonstrate the effect of low-intensity microwave radiation on levels of monoamine neurotransmitters and gene expression of their key regulating enzymes in brain of Fischer rats. Animals were exposed to 900 MHz and 1800 MHz microwave radiation for 30 days (2 h/day, 5 days/week) with respective specific absorption rates as 5.953 × 10(-4) and 5.835 × 10(-4) W/kg. The levels of monoamine neurotransmitters viz. dopamine (DA), norepinephrine (NE), epinephrine (E) and serotonin (5-HT) were detected using LC-MS/MS in hippocampus of all experimental animals. In addition, mRNA expression of key regulating enzymes for these neurotransmitters viz. tyrosine hydroxylase (TH) (for DA, NE and E) and tryptophan hydroxylase (TPH1 and TPH2) (for serotonin) was also estimated. Results showed significant reduction in levels of DA, NE, E and 5-HT in hippocampus of microwave-exposed animals in comparison with sham-exposed (control) animals. In addition, significant downregulation in mRNA expression of TH, TPH1 and TPH2 was also observed in microwave-exposed animals (p < 0.05). In conclusion, the results indicate that low-intensity microwave radiation may cause learning and memory disturbances by altering levels of brain monoamine neurotransmitters at mRNA and protein levels. |
X Demographics
The data shown below were collected from the profiles of 13 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 23% |
| Australia | 2 | 15% |
| Netherlands | 1 | 8% |
| Germany | 1 | 8% |
| United Kingdom | 1 | 8% |
| Unknown | 5 | 38% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 13 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Belgium | 1 | 3% |
| Unknown | 32 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 9 | 27% |
| Researcher | 7 | 21% |
| Student > Master | 3 | 9% |
| Student > Postgraduate | 2 | 6% |
| Student > Doctoral Student | 1 | 3% |
| Other | 4 | 12% |
| Unknown | 7 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 4 | 12% |
| Agricultural and Biological Sciences | 4 | 12% |
| Environmental Science | 3 | 9% |
| Neuroscience | 3 | 9% |
| Engineering | 3 | 9% |
| Other | 7 | 21% |
| Unknown | 9 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 September 2023.
All research outputs
#2,393,796
of 24,393,299 outputs
Outputs from Cell Biochemistry and Biophysics
#10
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Outputs of similar age
#34,957
of 366,759 outputs
Outputs of similar age from Cell Biochemistry and Biophysics
#2
of 110 outputs
Altmetric has tracked 24,393,299 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 945 research outputs from this source. They receive a mean Attention Score of 2.1. This one has done particularly well, scoring higher than 99% of its peers.
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We're also able to compare this research output to 110 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.