| Title |
Growth-phase dependent differential gene expression in Synechocystis sp. strain PCC 6803 and regulation by a group 2 sigma factor
|
|---|---|
| Published in |
Archives of Microbiology, December 2006
|
| DOI | 10.1007/s00203-006-0193-6 |
| Pubmed ID | |
| Authors |
Jamie S. Foster, Abhay K. Singh, Lynn J. Rothschild, Louis A. Sherman |
| Abstract |
Cyanobacteria must continually alter their physiological growth state in response to changes in light intensity and their nutritional and physical environment. Under typical laboratory batch growth conditions, cyanobacteria grow exponentially, then transition to a light-limited stage of linear growth before finally reaching a non-growth stationary phase. In this study, we utilized DNA microarrays to profile the expression of genes in the cyanobacterium Synechocystis sp. PCC 6803 to compare exponential and linear growth. We also studied the importance of SigB, a group 2 sigma factor in this cyanobacterium, during the different growth phases. The transcription of approximately 10% of the genes in the wild type were different in the linear, compared to the exponential phase, and our results showed that: (1) many photosynthesis and regulatory genes had lowered transcript levels; (2) individual genes, such as sigH, phrA, and isiA, which encode a group 4 sigma factor, a DNA photolyase, and a Chl-binding protein, respectively, were strongly induced; and, (3) the loss of SigB significantly impacted the differential expression of genes and modulated the changes seen in the wild type in regard to photosynthesis, regulatory and the unknown genes. |
Mendeley readers
The data shown below were compiled from readership statistics for 89 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 1% |
| Sweden | 1 | 1% |
| Czechia | 1 | 1% |
| France | 1 | 1% |
| Unknown | 85 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 22 | 25% |
| Researcher | 18 | 20% |
| Student > Master | 8 | 9% |
| Student > Doctoral Student | 7 | 8% |
| Professor | 5 | 6% |
| Other | 20 | 22% |
| Unknown | 9 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 38 | 43% |
| Biochemistry, Genetics and Molecular Biology | 21 | 24% |
| Environmental Science | 6 | 7% |
| Chemical Engineering | 2 | 2% |
| Social Sciences | 2 | 2% |
| Other | 8 | 9% |
| Unknown | 12 | 13% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 May 2023.
All research outputs
#7,814,012
of 23,717,467 outputs
Outputs from Archives of Microbiology
#595
of 2,919 outputs
Outputs of similar age
#42,909
of 159,847 outputs
Outputs of similar age from Archives of Microbiology
#2
of 6 outputs
Altmetric has tracked 23,717,467 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,919 research outputs from this source. They receive a mean Attention Score of 3.7. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
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We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.