| Title |
Microbial keratinases and their prospective applications: an overview
|
|---|---|
| Published in |
Applied Microbiology and Biotechnology, January 2006
|
| DOI | 10.1007/s00253-005-0239-8 |
| Pubmed ID | |
| Authors |
Rani Gupta, Priya Ramnani |
| Abstract |
Microbial keratinases have become biotechnologically important since they target the hydrolysis of highly rigid, strongly cross-linked structural polypeptide "keratin" recalcitrant to the commonly known proteolytic enzymes trypsin, pepsin and papain. These enzymes are largely produced in the presence of keratinous substrates in the form of hair, feather, wool, nail, horn etc. during their degradation. The complex mechanism of keratinolysis involves cooperative action of sulfitolytic and proteolytic systems. Keratinases are robust enzymes with a wide temperature and pH activity range and are largely serine or metallo proteases. Sequence homologies of keratinases indicate their relatedness to subtilisin family of serine proteases. They stand out among proteases since they attack the keratin residues and hence find application in developing cost-effective feather by-products for feed and fertilizers. Their application can also be extended to detergent and leather industries where they serve as specialty enzymes. Besides, they also find application in wool and silk cleaning; in the leather industry, better dehairing potential of these enzymes has led to the development of greener hair-saving dehairing technology and personal care products. Further, their prospective application in the challenging field of prion degradation would revolutionize the protease world in the near future. |
Mendeley readers
The data shown below were compiled from readership statistics for 365 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 2 | <1% |
| India | 2 | <1% |
| Chile | 1 | <1% |
| Germany | 1 | <1% |
| Spain | 1 | <1% |
| Unknown | 358 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 72 | 20% |
| Student > Master | 53 | 15% |
| Student > Bachelor | 53 | 15% |
| Researcher | 36 | 10% |
| Student > Doctoral Student | 11 | 3% |
| Other | 36 | 10% |
| Unknown | 104 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 100 | 27% |
| Biochemistry, Genetics and Molecular Biology | 49 | 13% |
| Chemistry | 22 | 6% |
| Engineering | 19 | 5% |
| Immunology and Microbiology | 17 | 5% |
| Other | 39 | 11% |
| Unknown | 119 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 October 2023.
All research outputs
#3,799,086
of 25,374,917 outputs
Outputs from Applied Microbiology and Biotechnology
#589
of 8,290 outputs
Outputs of similar age
#12,840
of 172,809 outputs
Outputs of similar age from Applied Microbiology and Biotechnology
#6
of 41 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,290 research outputs from this source. They receive a mean Attention Score of 4.4. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 172,809 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 41 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.