| Title |
The role of M1 muscarinic receptor agonism of N-desmethylclozapine in the unique clinical effects of clozapine
|
|---|---|
| Published in |
Psychopharmacology, July 2004
|
| DOI | 10.1007/s00213-004-1940-5 |
| Pubmed ID | |
| Authors |
D. M. Weiner, H. Y. Meltzer, I. Veinbergs, E. M. Donohue, T. A. Spalding, T. T. Smith, N. Mohell, S. C. Harvey, J. Lameh, N. Nash, K. E. Vanover, R. Olsson, K. Jayathilake, M. Lee, A. I. Levey, U. Hacksell, E. S. Burstein, R. E. Davis, M. R. Brann |
| Abstract |
Clozapine is a unique antipsychotic, with efficacy against positive symptoms in treatment-resistant schizophrenic patients, and the ability to improve cognition and treat the negative symptoms characteristic of this disease. Despite its unique clinical actions, no specific molecular mechanism responsible for these actions has yet been described. |
Mendeley readers
The data shown below were compiled from readership statistics for 119 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Germany | 1 | <1% |
| Austria | 1 | <1% |
| Unknown | 116 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 30 | 25% |
| Student > Ph. D. Student | 19 | 16% |
| Student > Master | 11 | 9% |
| Student > Bachelor | 11 | 9% |
| Student > Doctoral Student | 6 | 5% |
| Other | 17 | 14% |
| Unknown | 25 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 19 | 16% |
| Agricultural and Biological Sciences | 19 | 16% |
| Medicine and Dentistry | 18 | 15% |
| Biochemistry, Genetics and Molecular Biology | 9 | 8% |
| Psychology | 8 | 7% |
| Other | 14 | 12% |
| Unknown | 32 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 May 2010.
All research outputs
#7,454,951
of 22,790,780 outputs
Outputs from Psychopharmacology
#2,099
of 5,346 outputs
Outputs of similar age
#18,679
of 54,066 outputs
Outputs of similar age from Psychopharmacology
#15
of 24 outputs
Altmetric has tracked 22,790,780 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,346 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.6. This one is in the 28th percentile – i.e., 28% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 54,066 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.