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Mendeley readers
Attention Score in Context
| Title |
Organization of the Pre-autophagosomal Structure Responsible for Autophagosome Formation
|
|---|---|
| Published in |
Molecular Biology of the Cell, February 2008
|
| DOI | 10.1091/mbc.e07-10-1048 |
| Pubmed ID | |
| Authors |
Tomoko Kawamata, Yoshiaki Kamada, Yukiko Kabeya, Takayuki Sekito, Yoshinori Ohsumi |
| Abstract |
Autophagy induced by nutrient depletion is involved in survival during starvation conditions. In addition to starvation-induced autophagy, the yeast Saccharomyces cerevisiae also has a constitutive autophagy-like system, the Cvt pathway. Among 31 autophagy-related (Atg) proteins, the function of Atg17, Atg29, and Atg31 is required specifically for autophagy. In this study, we investigated the role of autophagy-specific (i.e., non-Cvt) proteins under autophagy-inducing conditions. For this purpose, we used atg11Delta cells in which the Cvt pathway is abrogated. The autophagy-unique proteins are required for the localization of Atg proteins to the pre-autophagosomal structure (PAS), the putative site for autophagosome formation, under starvation condition. It is likely that these Atg proteins function as a ternary complex, because Atg29 and Atg31 bind to Atg17. The Atg1 kinase complex (Atg1-Atg13) is also essential for recruitment of Atg proteins to the PAS. The assembly of Atg proteins to the PAS is observed only under autophagy-inducing conditions, indicating that this structure is specifically involved in autophagosome formation. Our results suggest that Atg1 complex and the autophagy-unique Atg proteins cooperatively organize the PAS in response to starvation signals. |
Mendeley readers
The data shown below were compiled from readership statistics for 179 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Hungary | 1 | <1% |
| Germany | 1 | <1% |
| Austria | 1 | <1% |
| Brazil | 1 | <1% |
| Finland | 1 | <1% |
| United Kingdom | 1 | <1% |
| Belgium | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 171 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 48 | 27% |
| Student > Master | 31 | 17% |
| Researcher | 18 | 10% |
| Student > Bachelor | 17 | 9% |
| Student > Doctoral Student | 7 | 4% |
| Other | 16 | 9% |
| Unknown | 42 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 69 | 39% |
| Biochemistry, Genetics and Molecular Biology | 45 | 25% |
| Medicine and Dentistry | 7 | 4% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 2% |
| Unspecified | 2 | 1% |
| Other | 8 | 4% |
| Unknown | 45 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 March 2010.
All research outputs
#8,535,472
of 25,374,647 outputs
Outputs from Molecular Biology of the Cell
#2,057
of 5,478 outputs
Outputs of similar age
#34,106
of 96,312 outputs
Outputs of similar age from Molecular Biology of the Cell
#17
of 45 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,478 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 36th percentile – i.e., 36% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 96,312 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 45 others from the same source and published within six weeks on either side of this one. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.